The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

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  Unconventional mechanisms for activating the NLRP3 inflammasome

  Vince, J. E. (Primary Chief Investigator (PCI)), Murphy, J. (Chief Investigator (CI)), Lawlor, K. (Chief Investigator (CI)) & Lindqvist, L. M. (Chief Investigator (CI))

  1/01/18 → 31/12/20

  Project: Research

• Interleukin-1b biology: mechanisms of regulation, activation and secretion

  Vince, J. E. (Primary Chief Investigator (PCI)), Masters, S. L. (Chief Investigator (CI)) & Harris, J. (Chief Investigator (CI))

  NHMRC - National Health and Medical Research Council (Australia)

  1/01/16 → 31/12/18

  Project: Research