The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

James E. Vince, Dominic De Nardo, Wenqing Gao, Angelina J. Vince, Cathrine Hall, Kate McArthur, Daniel Simpson, Swarna Vijayaraj, Lisa M. Lindqvist, Philippe Bouillet, Mark A. Rizzacasa, Si Ming Man, John Silke, Seth L. Masters, Guillaume Lessene, David C.S. Huang, Daniel H.D. Gray, Benjamin T. Kile, Feng Shao, Kate E. Lawlor

Research output: Contribution to journal › Article › Research › peer-review

175 Citations (Scopus)

2 results

Finished

Unconventional mechanisms for activating the NLRP3 inflammasome
Vince, J., Murphy, J., Lawlor, K. & Lindqvist, L. M.
1/01/18 → 31/12/20
Project: Research
Interleukin-1b biology: mechanisms of regulation, activation and secretion
Vince, J., Masters, S. L. & Harris, J.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/16 → 31/12/18
Project: Research