The macrolide-lincosamide-streptogramin B resistance determinant from Clostridium difficile 630 contains two erm(B) genes

Kylie A. Farrow, Dena Lyras, Julian I. Rood

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Abstract

The ErmB macrolide-lincosamide-streptogramin B (MLS) resistance determinant from Clostridium difficile 630 contains two copies of an erm(B) gene, separated by a 1.34-kb direct repeat also found in an Erm(B) determinant from Clostridium perfringens. In addition, both erm(B) genes are flanked by variants of the direct repeat sequence. This genetic arrangement is novel for an ErmB MLS resistance determinant.

Original languageEnglish
Pages (from-to)411-413
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume44
Issue number2
DOIs
Publication statusPublished - 1 Feb 2000

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