TY - JOUR
T1 - The long chain metabolites of linoleic and linolenic acids in liver and brain in herbivores and carnivores
AU - Crawford, M. A.
AU - Casperd, N. M.
AU - Sinclair, A. J.
PY - 1976/1/1
Y1 - 1976/1/1
N2 - 1. 1. The parent vegetable polyenoic acids and their long-chain animal metabolites have been studied in liver and brain phospholipids in a herbivorous mammal (Kob) and a carnivore (Hyaena) of similar body size, but contrasting developments of the nervous system. 2. 2. The fatty acid patterns of the phospholipids were found to be tissue and species specific. 3. 3. The major metabolite of linolenic acid was docosapentaenoate (C22:5,n-3) in the Kob liver, but docosahexaenoate (C22:6,n-3) in the Hyaena. Brain grey matter of both species contained the hexaenoate. 4. 4. Comparative studies from 30 different species demonstrated that the brain ethanolamine phosphoglycerides (EPG) had a relatively constant fatty acid composition despite wide variations in the fatty acid composition of liver EPG.
AB - 1. 1. The parent vegetable polyenoic acids and their long-chain animal metabolites have been studied in liver and brain phospholipids in a herbivorous mammal (Kob) and a carnivore (Hyaena) of similar body size, but contrasting developments of the nervous system. 2. 2. The fatty acid patterns of the phospholipids were found to be tissue and species specific. 3. 3. The major metabolite of linolenic acid was docosapentaenoate (C22:5,n-3) in the Kob liver, but docosahexaenoate (C22:6,n-3) in the Hyaena. Brain grey matter of both species contained the hexaenoate. 4. 4. Comparative studies from 30 different species demonstrated that the brain ethanolamine phosphoglycerides (EPG) had a relatively constant fatty acid composition despite wide variations in the fatty acid composition of liver EPG.
UR - http://www.scopus.com/inward/record.url?scp=0017161742&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(76)90264-9
DO - 10.1016/0305-0491(76)90264-9
M3 - Article
C2 - 1277808
AN - SCOPUS:0017161742
VL - 54
SP - 395
EP - 401
JO - Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
JF - Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology
SN - 1096-4959
IS - 3
ER -