The linac coherent light source single particle imaging road map

A. Aquila; A. Barty; C. Bostedt; S. Boutet; G. Carini; D. dePonte; P. Drell; S. Doniach; K. H. Downing; T. Earnest; H. Elmlund; V. Elser; M. Guhr; J. Hajdu; J. Hastings; S. P. Hau-Riege; Z. Huang; E. E. Lattman; F. R. N. C. Maia; S. Marchesini; A. Ourmazd; C. Pellegrini; R. Santra; I. Schlichting; C. Schroer; J. C. H. Spence; I. A. Vartanyants; S. Wakatsuki; W. I. Weis; G. J. Williams

doi:10.1063/1.4918726

The linac coherent light source single particle imaging road map

A. Aquila, A. Barty, C. Bostedt, S. Boutet, G. Carini, D. dePonte, P. Drell, S. Doniach, K. H. Downing, T. Earnest, H. Elmlund, V. Elser, M. Guhr, J. Hajdu, J. Hastings, S. P. Hau-Riege, Z. Huang, E. E. Lattman, F. R. N. C. Maia, S. MarchesiniA. Ourmazd, C. Pellegrini, R. Santra, I. Schlichting, C. Schroer, J. C. H. Spence, I. A. Vartanyants, S. Wakatsuki, W. I. Weis, G. J. Williams

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › Research › peer-review

173 Citations (Scopus)

Abstract

Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at the Linac Coherent Light Source (LCLS) have led to rapid progress in the field and, so far, coherent diffractive images have been recorded from biological specimens, aerosols, and quantum systems with a few-tens-of-nanometers resolution. In March 2014, LCLS held a workshop to discuss the scientific and technical challenges for reaching the ultimate goal of atomic resolution with single-shot coherent diffractive imaging. This paper summarizes the workshop findings and presents the roadmap toward reaching atomic resolution, 3D imaging at free-electron laser sources.

Original language	English
Article number	041701
Number of pages	13
Journal	Structural Dynamics
Volume	2
DOIs	https://doi.org/10.1063/1.4918726
Publication status	Published - Apr 2015

Keywords

photons
x-ray scattering
free electron lasers
image reconstruction
x-ray imaging

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10.1063/1.4918726

3555575-oaFinal published version, 120 KB

ARC Centre of Excellence in Advanced Molecular Imaging
Whisstock, J., Abbey, B., Nugent, K., Quiney, H. M., Godfrey, D. I., Heath, W., Fairlie, D., Chapman, H., Peele, A., Davey, J. & Wittmann, A.
30/06/14 → 31/03/21
Project: Research

Australian Synchrotron
Office of the Vice-Provost (Research and Research Infrastructure)
Facility/equipment: Facility

Cite this

Aquila, A., Barty, A., Bostedt, C., Boutet, S., Carini, G., dePonte, D., Drell, P., Doniach, S., Downing, K. H., Earnest, T., Elmlund, H., Elser, V., Guhr, M., Hajdu, J., Hastings, J., Hau-Riege, S. P., Huang, Z., Lattman, E. E., Maia, F. R. N. C., ... Williams, G. J. (2015). The linac coherent light source single particle imaging road map. Structural Dynamics, 2, Article 041701. https://doi.org/10.1063/1.4918726

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title = "The linac coherent light source single particle imaging road map",

abstract = "Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at the Linac Coherent Light Source (LCLS) have led to rapid progress in the field and, so far, coherent diffractive images have been recorded from biological specimens, aerosols, and quantum systems with a few-tens-of-nanometers resolution. In March 2014, LCLS held a workshop to discuss the scientific and technical challenges for reaching the ultimate goal of atomic resolution with single-shot coherent diffractive imaging. This paper summarizes the workshop findings and presents the roadmap toward reaching atomic resolution, 3D imaging at free-electron laser sources.",

keywords = "photons, x-ray scattering, free electron lasers, image reconstruction, x-ray imaging",

author = "A. Aquila and A. Barty and C. Bostedt and S. Boutet and G. Carini and D. dePonte and P. Drell and S. Doniach and Downing, {K. H.} and T. Earnest and H. Elmlund and V. Elser and M. Guhr and J. Hajdu and J. Hastings and Hau-Riege, {S. P.} and Z. Huang and Lattman, {E. E.} and Maia, {F. R. N. C.} and S. Marchesini and A. Ourmazd and C. Pellegrini and R. Santra and I. Schlichting and C. Schroer and Spence, {J. C. H.} and Vartanyants, {I. A.} and S. Wakatsuki and Weis, {W. I.} and Williams, {G. J.}",

year = "2015",

month = apr,

doi = "10.1063/1.4918726",

language = "English",

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journal = "Structural Dynamics",

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Aquila, A, Barty, A, Bostedt, C, Boutet, S, Carini, G, dePonte, D, Drell, P, Doniach, S, Downing, KH, Earnest, T, Elmlund, H, Elser, V, Guhr, M, Hajdu, J, Hastings, J, Hau-Riege, SP, Huang, Z, Lattman, EE, Maia, FRNC, Marchesini, S, Ourmazd, A, Pellegrini, C, Santra, R, Schlichting, I, Schroer, C, Spence, JCH, Vartanyants, IA, Wakatsuki, S, Weis, WI & Williams, GJ 2015, 'The linac coherent light source single particle imaging road map', Structural Dynamics, vol. 2, 041701. https://doi.org/10.1063/1.4918726

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AU - Aquila, A.

AU - Barty, A.

AU - Bostedt, C.

AU - Boutet, S.

AU - Carini, G.

AU - dePonte, D.

AU - Drell, P.

AU - Doniach, S.

AU - Downing, K. H.

AU - Earnest, T.

AU - Elmlund, H.

AU - Elser, V.

AU - Guhr, M.

AU - Hajdu, J.

AU - Hastings, J.

AU - Hau-Riege, S. P.

AU - Huang, Z.

AU - Lattman, E. E.

AU - Maia, F. R. N. C.

AU - Marchesini, S.

AU - Ourmazd, A.

AU - Pellegrini, C.

AU - Santra, R.

AU - Schlichting, I.

AU - Schroer, C.

AU - Spence, J. C. H.

AU - Vartanyants, I. A.

AU - Wakatsuki, S.

AU - Weis, W. I.

AU - Williams, G. J.

PY - 2015/4

Y1 - 2015/4

N2 - Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at the Linac Coherent Light Source (LCLS) have led to rapid progress in the field and, so far, coherent diffractive images have been recorded from biological specimens, aerosols, and quantum systems with a few-tens-of-nanometers resolution. In March 2014, LCLS held a workshop to discuss the scientific and technical challenges for reaching the ultimate goal of atomic resolution with single-shot coherent diffractive imaging. This paper summarizes the workshop findings and presents the roadmap toward reaching atomic resolution, 3D imaging at free-electron laser sources.

AB - Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at the Linac Coherent Light Source (LCLS) have led to rapid progress in the field and, so far, coherent diffractive images have been recorded from biological specimens, aerosols, and quantum systems with a few-tens-of-nanometers resolution. In March 2014, LCLS held a workshop to discuss the scientific and technical challenges for reaching the ultimate goal of atomic resolution with single-shot coherent diffractive imaging. This paper summarizes the workshop findings and presents the roadmap toward reaching atomic resolution, 3D imaging at free-electron laser sources.

KW - photons

KW - x-ray scattering

KW - free electron lasers

KW - image reconstruction

KW - x-ray imaging

U2 - 10.1063/1.4918726

DO - 10.1063/1.4918726

M3 - Article

SN - 2329-7778

VL - 2

JO - Structural Dynamics

JF - Structural Dynamics

M1 - 041701

ER -

The linac coherent light source single particle imaging road map

Abstract

Keywords

Access to Document

Projects

ARC Centre of Excellence in Advanced Molecular Imaging

Equipment

Australian Synchrotron

Cite this