The limitations of polymerase chain reaction in the setting of possible recurrent tuberculosis: 2 instructional cases

Thomas R. Schulz; Alan C. Street; Emma S. McBryde

doi:10.1016/j.diagmicrobio.2010.07.022

The limitations of polymerase chain reaction in the setting of possible recurrent tuberculosis: 2 instructional cases

Thomas R. Schulz, Alan C. Street, Emma S. McBryde

Research output: Contribution to journal › Article › Other › peer-review

Abstract

The interpretation of a positive result for Mycobacterium tuberculosis by nucleic acid amplification such as polymerase chain reaction (PCR) can be challenging. We present 2 cases that illustrate the limitations of tuberculosis PCR on respiratory secretions in previously treated patients, even years after the previous disease episode.

Original language	English
Pages (from-to)	293-296
Number of pages	4
Journal	Diagnostic Microbiology and Infectious Disease
Volume	68
Issue number	3
DOIs	https://doi.org/10.1016/j.diagmicrobio.2010.07.022
Publication status	Published - Nov 2010
Externally published	Yes

Keywords

False positive
Nucleic Acid Testing
Polymerase Chain Reaction
Tuberculosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.diagmicrobio.2010.07.022

Cite this

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title = "The limitations of polymerase chain reaction in the setting of possible recurrent tuberculosis: 2 instructional cases",

abstract = "The interpretation of a positive result for Mycobacterium tuberculosis by nucleic acid amplification such as polymerase chain reaction (PCR) can be challenging. We present 2 cases that illustrate the limitations of tuberculosis PCR on respiratory secretions in previously treated patients, even years after the previous disease episode.",

keywords = "False positive, Nucleic Acid Testing, Polymerase Chain Reaction, Tuberculosis",

author = "Schulz, \{Thomas R.\} and Street, \{Alan C.\} and McBryde, \{Emma S.\}",

year = "2010",

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language = "English",

volume = "68",

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journal = "Diagnostic Microbiology and Infectious Disease",

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TY - JOUR

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T2 - 2 instructional cases

AU - Schulz, Thomas R.

AU - Street, Alan C.

AU - McBryde, Emma S.

PY - 2010/11

Y1 - 2010/11

N2 - The interpretation of a positive result for Mycobacterium tuberculosis by nucleic acid amplification such as polymerase chain reaction (PCR) can be challenging. We present 2 cases that illustrate the limitations of tuberculosis PCR on respiratory secretions in previously treated patients, even years after the previous disease episode.

AB - The interpretation of a positive result for Mycobacterium tuberculosis by nucleic acid amplification such as polymerase chain reaction (PCR) can be challenging. We present 2 cases that illustrate the limitations of tuberculosis PCR on respiratory secretions in previously treated patients, even years after the previous disease episode.

KW - False positive

KW - Nucleic Acid Testing

KW - Polymerase Chain Reaction

KW - Tuberculosis

UR - https://www.scopus.com/pages/publications/77957922963

U2 - 10.1016/j.diagmicrobio.2010.07.022

DO - 10.1016/j.diagmicrobio.2010.07.022

M3 - Article

C2 - 20955913

AN - SCOPUS:77957922963

SN - 0732-8893

VL - 68

SP - 293

EP - 296

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 3

ER -

The limitations of polymerase chain reaction in the setting of possible recurrent tuberculosis: 2 instructional cases

Abstract

Keywords

UN SDGs

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