Bacteriocins are ribosomally synthesised antimicrobial proteins produced by bacteria that generally kill or inhibit species or strains closely related to the producer. Members of the genus Streptococcus produce a myriad of bacteriocins, most of which are small (< 6 kDa) peptides. However, several large (> 10 kDa) streptococcal bacteriocins have also been identified. In this paper, we describe the biochemical and genetic characteristics of the large bacteriocins currently studied in our laboratory, including the identification of stellalysin, a new lytic bacteriocin produced by Streptococcus constellatus subsp. constellatus.
- Antimicrobial protein
- Streptococcin A-M57