The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

Moritoki Egi; Hiroshi Ogura; Tomoaki Yatabe; Kazuaki Atagi; Shigeaki Inoue; Toshiaki Iba; Yasuyuki Kakihana; Tatsuya Kawasaki; Shigeki Kushimoto; Yasuhiro Kuroda; Joji Kotani; Nobuaki Shime; Takumi Taniguchi; Ryosuke Tsuruta; Kent Doi; Matsuyuki Doi; Taka aki Nakada; Masaki Nakane; Seitaro Fujishima; Naoto Hosokawa; Yoshiki Masuda; Asako Matsushima; Naoyuki Matsuda; Kazuma Yamakawa; Yoshitaka Hara; Masaaki Sakuraya; Shinichiro Ohshimo; Yoshitaka Aoki; Mai Inada; Yutaka Umemura; Yusuke Kawai; Yutaka Kondo; Hiroki Saito; Shunsuke Taito; Chikashi Takeda; Takero Terayama; Hideo Tohira; Hideki Hashimoto; Kei Hayashida; Toru Hifumi; Tomoya Hirose; Tatsuma Fukuda; Tomoko Fujii; Shinya Miura; Hideto Yasuda; Toshikazu Abe; Kohkichi Andoh; Yuki Iida; Tadashi Ishihara; Kentaro Ide; Kenta Ito; Yusuke Ito; Yu Inata; Akemi Utsunomiya; Takeshi Unoki; Koji Endo; Akira Ouchi; Masayuki Ozaki; Satoshi Ono; Morihiro Katsura; Atsushi Kawaguchi; Yusuke Kawamura; Daisuke Kudo; Kenji Kubo; Kiyoyasu Kurahashi; Hideaki Sakuramoto; Akira Shimoyama; Takeshi Suzuki; Shusuke Sekine; Motohiro Sekino; Nozomi Takahashi; Sei Takahashi; Hiroshi Takahashi; Takashi Tagami; Goro Tajima; Hiroomi Tatsumi; Masanori Tani; Asuka Tsuchiya; Yusuke Tsutsumi; Takaki Naito; Masaharu Nagae; Ichiro Nagasawa; Kensuke Nakamura; Tetsuro Nishimura; Shin Nunomiya; Yasuhiro Norisue; Satoru Hashimoto; Daisuke Hasegawa; Junji Hatakeyama; Naoki Hara; Naoki Higashibeppu; Nana Furushima; Hirotaka Furusono; Yujiro Matsuishi; Tasuku Matsuyama; Yusuke Minematsu; Ryoichi Miyashita; Yuji Miyatake; Megumi Moriyasu; Toru Yamada; Hiroyuki Yamada; Ryo Yamamoto; Takeshi Yoshida; Yuhei Yoshida; Jumpei Yoshimura; Ryuichi Yotsumoto; Hiroshi Yonekura; Takeshi Wada; Eizo Watanabe; Makoto Aoki; Hideki Asai; Takakuni Abe; Yutaka Igarashi; Naoya Iguchi; Masami Ishikawa; Go Ishimaru; Shutaro Isokawa; Ryuta Itakura; Hisashi Imahase; Haruki Imura; Takashi Irinoda; Kenji Uehara; Noritaka Ushio; Takeshi Umegaki; Yuko Egawa; Yuki Enomoto; Kohei Ota; Yoshifumi Ohchi; Takanori Ohno; Hiroyuki Ohbe; Kazuyuki Oka; Nobunaga Okada; Yohei Okada; Hiromu Okano; Jun Okamoto; Hiroshi Okuda; Takayuki Ogura; Yu Onodera; Yuhta Oyama; Motoshi Kainuma; Eisuke Kako; Masahiro Kashiura; Hiromi Kato; Akihiro Kanaya; Tadashi Kaneko; Keita Kanehata; Ken ichi Kano; Hiroyuki Kawano; Kazuya Kikutani; Hitoshi Kikuchi; Takahiro Kido; Sho Kimura; Hiroyuki Koami; Daisuke Kobashi; Iwao Saiki; Masahito Sakai; Ayaka Sakamoto; Tetsuya Sato; Yasuhiro Shiga; Manabu Shimoto; Shinya Shimoyama; Tomohisa Shoko; Yoh Sugawara; Atsunori Sugita; Satoshi Suzuki; Yuji Suzuki; Tomohiro Suhara; Kenji Sonota; Shuhei Takauji; Kohei Takashima; Sho Takahashi; Yoko Takahashi; Jun Takeshita; Yuuki Tanaka; Akihito Tampo; Taichiro Tsunoyama; Kenichi Tetsuhara; Kentaro Tokunaga; Yoshihiro Tomioka; Kentaro Tomita; Naoki Tominaga; Mitsunobu Toyosaki; Yukitoshi Toyoda; Hiromichi Naito; Isao Nagata; Tadashi Nagato; Yoshimi Nakamura; Yuki Nakamori; Isao Nahara; Hiromu Naraba; Chihiro Narita; Norihiro Nishioka; Tomoya Nishimura; Kei Nishiyama; Tomohisa Nomura; Taiki Haga; Yoshihiro Hagiwara; Katsuhiko Hashimoto; Takeshi Hatachi; Toshiaki Hamasaki; Takuya Hayashi; Minoru Hayashi; Atsuki Hayamizu; Go Haraguchi; Yohei Hirano; Ryo Fujii; Motoki Fujita; Naoyuki Fujimura; Hiraku Funakoshi; Masahito Horiguchi; Jun Maki; Naohisa Masunaga; Yosuke Matsumura; Takuya Mayumi; Keisuke Minami; Yuya Miyazaki; Kazuyuki Miyamoto; Teppei Murata; Machi Yanai; Takao Yano; Kohei Yamada; Naoki Yamada; Tomonori Yamamoto; Shodai Yoshihiro; Hiroshi Tanaka; Osamu Nishida

doi:10.1186/s40560-021-00555-7

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

Moritoki Egi, Hiroshi Ogura, Tomoaki Yatabe, Kazuaki Atagi, Shigeaki Inoue, Toshiaki Iba, Yasuyuki Kakihana, Tatsuya Kawasaki, Shigeki Kushimoto, Yasuhiro Kuroda, Joji Kotani, Nobuaki Shime, Takumi Taniguchi, Ryosuke Tsuruta, Kent Doi, Matsuyuki Doi, Taka aki Nakada, Masaki Nakane, Seitaro Fujishima, Naoto HosokawaYoshiki Masuda, Asako Matsushima, Naoyuki Matsuda, Kazuma Yamakawa, Yoshitaka Hara, Masaaki Sakuraya, Shinichiro Ohshimo, Yoshitaka Aoki, Mai Inada, Yutaka Umemura, Yusuke Kawai, Yutaka Kondo, Hiroki Saito, Shunsuke Taito, Chikashi Takeda, Takero Terayama, Hideo Tohira, Hideki Hashimoto, Kei Hayashida, Toru Hifumi, Tomoya Hirose, Tatsuma Fukuda, Tomoko Fujii, Shinya Miura, Hideto Yasuda, Toshikazu Abe, Kohkichi Andoh, Yuki Iida, Tadashi Ishihara, Kentaro Ide, Kenta Ito, Yusuke Ito, Yu Inata, Akemi Utsunomiya, Takeshi Unoki, Koji Endo, Akira Ouchi, Masayuki Ozaki, Satoshi Ono, Morihiro Katsura, Atsushi Kawaguchi, Yusuke Kawamura, Daisuke Kudo, Kenji Kubo, Kiyoyasu Kurahashi, Hideaki Sakuramoto, Akira Shimoyama, Takeshi Suzuki, Shusuke Sekine, Motohiro Sekino, Nozomi Takahashi, Sei Takahashi, Hiroshi Takahashi, Takashi Tagami, Goro Tajima, Hiroomi Tatsumi, Masanori Tani, Asuka Tsuchiya, Yusuke Tsutsumi, Takaki Naito, Masaharu Nagae, Ichiro Nagasawa, Kensuke Nakamura, Tetsuro Nishimura, Shin Nunomiya, Yasuhiro Norisue, Satoru Hashimoto, Daisuke Hasegawa, Junji Hatakeyama, Naoki Hara, Naoki Higashibeppu, Nana Furushima, Hirotaka Furusono, Yujiro Matsuishi, Tasuku Matsuyama, Yusuke Minematsu, Ryoichi Miyashita, Yuji Miyatake, Megumi Moriyasu, Toru Yamada, Hiroyuki Yamada, Ryo Yamamoto, Takeshi Yoshida, Yuhei Yoshida, Jumpei Yoshimura, Ryuichi Yotsumoto, Hiroshi Yonekura, Takeshi Wada, Eizo Watanabe, Makoto Aoki, Hideki Asai, Takakuni Abe, Yutaka Igarashi, Naoya Iguchi, Masami Ishikawa, Go Ishimaru, Shutaro Isokawa, Ryuta Itakura, Hisashi Imahase, Haruki Imura, Takashi Irinoda, Kenji Uehara, Noritaka Ushio, Takeshi Umegaki, Yuko Egawa, Yuki Enomoto, Kohei Ota, Yoshifumi Ohchi, Takanori Ohno, Hiroyuki Ohbe, Kazuyuki Oka, Nobunaga Okada, Yohei Okada, Hiromu Okano, Jun Okamoto, Hiroshi Okuda, Takayuki Ogura, Yu Onodera, Yuhta Oyama, Motoshi Kainuma, Eisuke Kako, Masahiro Kashiura, Hiromi Kato, Akihiro Kanaya, Tadashi Kaneko, Keita Kanehata, Ken ichi Kano, Hiroyuki Kawano, Kazuya Kikutani, Hitoshi Kikuchi, Takahiro Kido, Sho Kimura, Hiroyuki Koami, Daisuke Kobashi, Iwao Saiki, Masahito Sakai, Ayaka Sakamoto, Tetsuya Sato, Yasuhiro Shiga, Manabu Shimoto, Shinya Shimoyama, Tomohisa Shoko, Yoh Sugawara, Atsunori Sugita, Satoshi Suzuki, Yuji Suzuki, Tomohiro Suhara, Kenji Sonota, Shuhei Takauji, Kohei Takashima, Sho Takahashi, Yoko Takahashi, Jun Takeshita, Yuuki Tanaka, Akihito Tampo, Taichiro Tsunoyama, Kenichi Tetsuhara, Kentaro Tokunaga, Yoshihiro Tomioka, Kentaro Tomita, Naoki Tominaga, Mitsunobu Toyosaki, Yukitoshi Toyoda, Hiromichi Naito, Isao Nagata, Tadashi Nagato, Yoshimi Nakamura, Yuki Nakamori, Isao Nahara, Hiromu Naraba, Chihiro Narita, Norihiro Nishioka, Tomoya Nishimura, Kei Nishiyama, Tomohisa Nomura, Taiki Haga, Yoshihiro Hagiwara, Katsuhiko Hashimoto, Takeshi Hatachi, Toshiaki Hamasaki, Takuya Hayashi, Minoru Hayashi, Atsuki Hayamizu, Go Haraguchi, Yohei Hirano, Ryo Fujii, Motoki Fujita, Naoyuki Fujimura, Hiraku Funakoshi, Masahito Horiguchi, Jun Maki, Naohisa Masunaga, Yosuke Matsumura, Takuya Mayumi, Keisuke Minami, Yuya Miyazaki, Kazuyuki Miyamoto, Teppei Murata, Machi Yanai, Takao Yano, Kohei Yamada, Naoki Yamada, Tomonori Yamamoto, Shodai Yoshihiro, Hiroshi Tanaka, Osamu Nishida

Research output: Contribution to journal › Article › Research › peer-review

47 Citations (Scopus)

Abstract

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created as revised from J-SSCG 2016 jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in September 2020 and published in February 2021. An English-language version of these guidelines was created based on the contents of the original Japanese-language version. The purpose of this guideline is to assist medical staff in making appropriate decisions to improve the prognosis of patients undergoing treatment for sepsis and septic shock. We aimed to provide high-quality guidelines that are easy to use and understand for specialists, general clinicians, and multidisciplinary medical professionals. J-SSCG 2016 took up new subjects that were not present in SSCG 2016 (e.g., ICU-acquired weakness [ICU-AW], post-intensive care syndrome [PICS], and body temperature management). The J-SSCG 2020 covered a total of 22 areas with four additional new areas (patient- and family-centered care, sepsis treatment system, neuro-intensive treatment, and stress ulcers). A total of 118 important clinical issues (clinical questions, CQs) were extracted regardless of the presence or absence of evidence. These CQs also include those that have been given particular focus within Japan. This is a large-scale guideline covering multiple fields; thus, in addition to the 25 committee members, we had the participation and support of a total of 226 members who are professionals (physicians, nurses, physiotherapists, clinical engineers, and pharmacists) and medical workers with a history of sepsis or critical illness. The GRADE method was adopted for making recommendations, and the modified Delphi method was used to determine recommendations by voting from all committee members. As a result, 79 GRADE-based recommendations, 5 Good Practice Statements (GPS), 18 expert consensuses, 27 answers to background questions (BQs), and summaries of definitions and diagnosis of sepsis were created as responses to 118 CQs. We also incorporated visual information for each CQ according to the time course of treatment, and we will also distribute this as an app. The J-SSCG 2020 is expected to be widely used as a useful bedside guideline in the field of sepsis treatment both in Japan and overseas involving multiple disciplines.

Original language	English
Article number	53
Number of pages	144
Journal	Journal of Intensive Care
Volume	9
Issue number	1
DOIs	https://doi.org/10.1186/s40560-021-00555-7
Publication status	Published - Dec 2021
Externally published	Yes

Keywords

Evidence-based medicine
GRADE
Guidelines
Sepsis
Septic shock
Systematic review

Access to Document

10.1186/s40560-021-00555-7Licence: CC BY

Cite this

Egi, M., Ogura, H., Yatabe, T., Atagi, K., Inoue, S., Iba, T., Kakihana, Y., Kawasaki, T., Kushimoto, S., Kuroda, Y., Kotani, J., Shime, N., Taniguchi, T., Tsuruta, R., Doi, K., Doi, M., Nakada, T. A., Nakane, M., Fujishima, S., ... Nishida, O. (2021). The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020). Journal of Intensive Care, 9(1), [53]. https://doi.org/10.1186/s40560-021-00555-7

@article{78618a55383c4569a2e07a85e360c396,

title = "The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)",

abstract = "The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created as revised from J-SSCG 2016 jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in September 2020 and published in February 2021. An English-language version of these guidelines was created based on the contents of the original Japanese-language version. The purpose of this guideline is to assist medical staff in making appropriate decisions to improve the prognosis of patients undergoing treatment for sepsis and septic shock. We aimed to provide high-quality guidelines that are easy to use and understand for specialists, general clinicians, and multidisciplinary medical professionals. J-SSCG 2016 took up new subjects that were not present in SSCG 2016 (e.g., ICU-acquired weakness [ICU-AW], post-intensive care syndrome [PICS], and body temperature management). The J-SSCG 2020 covered a total of 22 areas with four additional new areas (patient- and family-centered care, sepsis treatment system, neuro-intensive treatment, and stress ulcers). A total of 118 important clinical issues (clinical questions, CQs) were extracted regardless of the presence or absence of evidence. These CQs also include those that have been given particular focus within Japan. This is a large-scale guideline covering multiple fields; thus, in addition to the 25 committee members, we had the participation and support of a total of 226 members who are professionals (physicians, nurses, physiotherapists, clinical engineers, and pharmacists) and medical workers with a history of sepsis or critical illness. The GRADE method was adopted for making recommendations, and the modified Delphi method was used to determine recommendations by voting from all committee members. As a result, 79 GRADE-based recommendations, 5 Good Practice Statements (GPS), 18 expert consensuses, 27 answers to background questions (BQs), and summaries of definitions and diagnosis of sepsis were created as responses to 118 CQs. We also incorporated visual information for each CQ according to the time course of treatment, and we will also distribute this as an app. The J-SSCG 2020 is expected to be widely used as a useful bedside guideline in the field of sepsis treatment both in Japan and overseas involving multiple disciplines.",

keywords = "Evidence-based medicine, GRADE, Guidelines, Sepsis, Septic shock, Systematic review",

author = "Moritoki Egi and Hiroshi Ogura and Tomoaki Yatabe and Kazuaki Atagi and Shigeaki Inoue and Toshiaki Iba and Yasuyuki Kakihana and Tatsuya Kawasaki and Shigeki Kushimoto and Yasuhiro Kuroda and Joji Kotani and Nobuaki Shime and Takumi Taniguchi and Ryosuke Tsuruta and Kent Doi and Matsuyuki Doi and Nakada, {Taka aki} and Masaki Nakane and Seitaro Fujishima and Naoto Hosokawa and Yoshiki Masuda and Asako Matsushima and Naoyuki Matsuda and Kazuma Yamakawa and Yoshitaka Hara and Masaaki Sakuraya and Shinichiro Ohshimo and Yoshitaka Aoki and Mai Inada and Yutaka Umemura and Yusuke Kawai and Yutaka Kondo and Hiroki Saito and Shunsuke Taito and Chikashi Takeda and Takero Terayama and Hideo Tohira and Hideki Hashimoto and Kei Hayashida and Toru Hifumi and Tomoya Hirose and Tatsuma Fukuda and Tomoko Fujii and Shinya Miura and Hideto Yasuda and Toshikazu Abe and Kohkichi Andoh and Yuki Iida and Tadashi Ishihara and Kentaro Ide and Kenta Ito and Yusuke Ito and Yu Inata and Akemi Utsunomiya and Takeshi Unoki and Koji Endo and Akira Ouchi and Masayuki Ozaki and Satoshi Ono and Morihiro Katsura and Atsushi Kawaguchi and Yusuke Kawamura and Daisuke Kudo and Kenji Kubo and Kiyoyasu Kurahashi and Hideaki Sakuramoto and Akira Shimoyama and Takeshi Suzuki and Shusuke Sekine and Motohiro Sekino and Nozomi Takahashi and Sei Takahashi and Hiroshi Takahashi and Takashi Tagami and Goro Tajima and Hiroomi Tatsumi and Masanori Tani and Asuka Tsuchiya and Yusuke Tsutsumi and Takaki Naito and Masaharu Nagae and Ichiro Nagasawa and Kensuke Nakamura and Tetsuro Nishimura and Shin Nunomiya and Yasuhiro Norisue and Satoru Hashimoto and Daisuke Hasegawa and Junji Hatakeyama and Naoki Hara and Naoki Higashibeppu and Nana Furushima and Hirotaka Furusono and Yujiro Matsuishi and Tasuku Matsuyama and Yusuke Minematsu and Ryoichi Miyashita and Yuji Miyatake and Megumi Moriyasu and Toru Yamada and Hiroyuki Yamada and Ryo Yamamoto and Takeshi Yoshida and Yuhei Yoshida and Jumpei Yoshimura and Ryuichi Yotsumoto and Hiroshi Yonekura and Takeshi Wada and Eizo Watanabe and Makoto Aoki and Hideki Asai and Takakuni Abe and Yutaka Igarashi and Naoya Iguchi and Masami Ishikawa and Go Ishimaru and Shutaro Isokawa and Ryuta Itakura and Hisashi Imahase and Haruki Imura and Takashi Irinoda and Kenji Uehara and Noritaka Ushio and Takeshi Umegaki and Yuko Egawa and Yuki Enomoto and Kohei Ota and Yoshifumi Ohchi and Takanori Ohno and Hiroyuki Ohbe and Kazuyuki Oka and Nobunaga Okada and Yohei Okada and Hiromu Okano and Jun Okamoto and Hiroshi Okuda and Takayuki Ogura and Yu Onodera and Yuhta Oyama and Motoshi Kainuma and Eisuke Kako and Masahiro Kashiura and Hiromi Kato and Akihiro Kanaya and Tadashi Kaneko and Keita Kanehata and Kano, {Ken ichi} and Hiroyuki Kawano and Kazuya Kikutani and Hitoshi Kikuchi and Takahiro Kido and Sho Kimura and Hiroyuki Koami and Daisuke Kobashi and Iwao Saiki and Masahito Sakai and Ayaka Sakamoto and Tetsuya Sato and Yasuhiro Shiga and Manabu Shimoto and Shinya Shimoyama and Tomohisa Shoko and Yoh Sugawara and Atsunori Sugita and Satoshi Suzuki and Yuji Suzuki and Tomohiro Suhara and Kenji Sonota and Shuhei Takauji and Kohei Takashima and Sho Takahashi and Yoko Takahashi and Jun Takeshita and Yuuki Tanaka and Akihito Tampo and Taichiro Tsunoyama and Kenichi Tetsuhara and Kentaro Tokunaga and Yoshihiro Tomioka and Kentaro Tomita and Naoki Tominaga and Mitsunobu Toyosaki and Yukitoshi Toyoda and Hiromichi Naito and Isao Nagata and Tadashi Nagato and Yoshimi Nakamura and Yuki Nakamori and Isao Nahara and Hiromu Naraba and Chihiro Narita and Norihiro Nishioka and Tomoya Nishimura and Kei Nishiyama and Tomohisa Nomura and Taiki Haga and Yoshihiro Hagiwara and Katsuhiko Hashimoto and Takeshi Hatachi and Toshiaki Hamasaki and Takuya Hayashi and Minoru Hayashi and Atsuki Hayamizu and Go Haraguchi and Yohei Hirano and Ryo Fujii and Motoki Fujita and Naoyuki Fujimura and Hiraku Funakoshi and Masahito Horiguchi and Jun Maki and Naohisa Masunaga and Yosuke Matsumura and Takuya Mayumi and Keisuke Minami and Yuya Miyazaki and Kazuyuki Miyamoto and Teppei Murata and Machi Yanai and Takao Yano and Kohei Yamada and Naoki Yamada and Tomonori Yamamoto and Shodai Yoshihiro and Hiroshi Tanaka and Osamu Nishida",

note = "Funding Information: These guidelines were prepared with financial support from the Japan Society of Intensive Care Medicine and the Japanese Association for Acute Medicine. No member of the Guideline Creation Committee received any form of financial compensation during the preparation of these guidelines. The views and interests of these societies were not reflected in the preparation of the guidelines{\textquoteright} recommendations. Funding Information: We would like to thank Minds for their guidance and support to create these guidelines, and Editage (www.editage.jp) for their English language editing service. We also gratefully acknowledge Dr. Masaaki Sakuraya for his contribution to the English version of J-SSCG2020 as the creation leader of the academic guideline promotion members, and Ms. Yumika Yoshida in the Japanese Society of Intensive Care Medicine Secretariat and Mr. Shuta Fukuda in the Japanese Association for Acute Medicine Secretariat for their kind supports. Publisher Copyright: {\textcopyright} 2021, The Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

year = "2021",

month = dec,

doi = "10.1186/s40560-021-00555-7",

language = "English",

volume = "9",

journal = "Journal of Intensive Care",

issn = "2052-0492",

publisher = "BioMed Central",

number = "1",

}

Egi, M, Ogura, H, Yatabe, T, Atagi, K, Inoue, S, Iba, T, Kakihana, Y, Kawasaki, T, Kushimoto, S, Kuroda, Y, Kotani, J, Shime, N, Taniguchi, T, Tsuruta, R, Doi, K, Doi, M, Nakada, TA, Nakane, M, Fujishima, S, Hosokawa, N, Masuda, Y, Matsushima, A, Matsuda, N, Yamakawa, K, Hara, Y, Sakuraya, M, Ohshimo, S, Aoki, Y, Inada, M, Umemura, Y, Kawai, Y, Kondo, Y, Saito, H, Taito, S, Takeda, C, Terayama, T, Tohira, H, Hashimoto, H, Hayashida, K, Hifumi, T, Hirose, T, Fukuda, T, Fujii, T, Miura, S, Yasuda, H, Abe, T, Andoh, K, Iida, Y, Ishihara, T, Ide, K, Ito, K, Ito, Y, Inata, Y, Utsunomiya, A, Unoki, T, Endo, K, Ouchi, A, Ozaki, M, Ono, S, Katsura, M, Kawaguchi, A, Kawamura, Y, Kudo, D, Kubo, K, Kurahashi, K, Sakuramoto, H, Shimoyama, A, Suzuki, T, Sekine, S, Sekino, M, Takahashi, N, Takahashi, S, Takahashi, H, Tagami, T, Tajima, G, Tatsumi, H, Tani, M, Tsuchiya, A, Tsutsumi, Y, Naito, T, Nagae, M, Nagasawa, I, Nakamura, K, Nishimura, T, Nunomiya, S, Norisue, Y, Hashimoto, S, Hasegawa, D, Hatakeyama, J, Hara, N, Higashibeppu, N, Furushima, N, Furusono, H, Matsuishi, Y, Matsuyama, T, Minematsu, Y, Miyashita, R, Miyatake, Y, Moriyasu, M, Yamada, T, Yamada, H, Yamamoto, R, Yoshida, T, Yoshida, Y, Yoshimura, J, Yotsumoto, R, Yonekura, H, Wada, T, Watanabe, E, Aoki, M, Asai, H, Abe, T, Igarashi, Y, Iguchi, N, Ishikawa, M, Ishimaru, G, Isokawa, S, Itakura, R, Imahase, H, Imura, H, Irinoda, T, Uehara, K, Ushio, N, Umegaki, T, Egawa, Y, Enomoto, Y, Ota, K, Ohchi, Y, Ohno, T, Ohbe, H, Oka, K, Okada, N, Okada, Y, Okano, H, Okamoto, J, Okuda, H, Ogura, T, Onodera, Y, Oyama, Y, Kainuma, M, Kako, E, Kashiura, M, Kato, H, Kanaya, A, Kaneko, T, Kanehata, K, Kano, KI, Kawano, H, Kikutani, K, Kikuchi, H, Kido, T, Kimura, S, Koami, H, Kobashi, D, Saiki, I, Sakai, M, Sakamoto, A, Sato, T, Shiga, Y, Shimoto, M, Shimoyama, S, Shoko, T, Sugawara, Y, Sugita, A, Suzuki, S, Suzuki, Y, Suhara, T, Sonota, K, Takauji, S, Takashima, K, Takahashi, S, Takahashi, Y, Takeshita, J, Tanaka, Y, Tampo, A, Tsunoyama, T, Tetsuhara, K, Tokunaga, K, Tomioka, Y, Tomita, K, Tominaga, N, Toyosaki, M, Toyoda, Y, Naito, H, Nagata, I, Nagato, T, Nakamura, Y, Nakamori, Y, Nahara, I, Naraba, H, Narita, C, Nishioka, N, Nishimura, T, Nishiyama, K, Nomura, T, Haga, T, Hagiwara, Y, Hashimoto, K, Hatachi, T, Hamasaki, T, Hayashi, T, Hayashi, M, Hayamizu, A, Haraguchi, G, Hirano, Y, Fujii, R, Fujita, M, Fujimura, N, Funakoshi, H, Horiguchi, M, Maki, J, Masunaga, N, Matsumura, Y, Mayumi, T, Minami, K, Miyazaki, Y, Miyamoto, K, Murata, T, Yanai, M, Yano, T, Yamada, K, Yamada, N, Yamamoto, T, Yoshihiro, S, Tanaka, H & Nishida, O 2021, 'The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)', Journal of Intensive Care, vol. 9, no. 1, 53. https://doi.org/10.1186/s40560-021-00555-7

TY - JOUR

T1 - The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

AU - Egi, Moritoki

AU - Ogura, Hiroshi

AU - Yatabe, Tomoaki

AU - Atagi, Kazuaki

AU - Inoue, Shigeaki

AU - Iba, Toshiaki

AU - Kakihana, Yasuyuki

AU - Kawasaki, Tatsuya

AU - Kushimoto, Shigeki

AU - Kuroda, Yasuhiro

AU - Kotani, Joji

AU - Shime, Nobuaki

AU - Taniguchi, Takumi

AU - Tsuruta, Ryosuke

AU - Doi, Kent

AU - Doi, Matsuyuki

AU - Nakada, Taka aki

AU - Nakane, Masaki

AU - Fujishima, Seitaro

AU - Hosokawa, Naoto

AU - Masuda, Yoshiki

AU - Matsushima, Asako

AU - Matsuda, Naoyuki

AU - Yamakawa, Kazuma

AU - Hara, Yoshitaka

AU - Sakuraya, Masaaki

AU - Ohshimo, Shinichiro

AU - Aoki, Yoshitaka

AU - Inada, Mai

AU - Umemura, Yutaka

AU - Kawai, Yusuke

AU - Kondo, Yutaka

AU - Saito, Hiroki

AU - Taito, Shunsuke

AU - Takeda, Chikashi

AU - Terayama, Takero

AU - Tohira, Hideo

AU - Hashimoto, Hideki

AU - Hayashida, Kei

AU - Hifumi, Toru

AU - Hirose, Tomoya

AU - Fukuda, Tatsuma

AU - Fujii, Tomoko

AU - Miura, Shinya

AU - Yasuda, Hideto

AU - Abe, Toshikazu

AU - Andoh, Kohkichi

AU - Iida, Yuki

AU - Ishihara, Tadashi

AU - Ide, Kentaro

AU - Ito, Kenta

AU - Ito, Yusuke

AU - Inata, Yu

AU - Utsunomiya, Akemi

AU - Unoki, Takeshi

AU - Endo, Koji

AU - Ouchi, Akira

AU - Ozaki, Masayuki

AU - Ono, Satoshi

AU - Katsura, Morihiro

AU - Kawaguchi, Atsushi

AU - Kawamura, Yusuke

AU - Kudo, Daisuke

AU - Kubo, Kenji

AU - Kurahashi, Kiyoyasu

AU - Sakuramoto, Hideaki

AU - Shimoyama, Akira

AU - Suzuki, Takeshi

AU - Sekine, Shusuke

AU - Sekino, Motohiro

AU - Takahashi, Nozomi

AU - Takahashi, Sei

AU - Takahashi, Hiroshi

AU - Tagami, Takashi

AU - Tajima, Goro

AU - Tatsumi, Hiroomi

AU - Tani, Masanori

AU - Tsuchiya, Asuka

AU - Tsutsumi, Yusuke

AU - Naito, Takaki

AU - Nagae, Masaharu

AU - Nagasawa, Ichiro

AU - Nakamura, Kensuke

AU - Nishimura, Tetsuro

AU - Nunomiya, Shin

AU - Norisue, Yasuhiro

AU - Hashimoto, Satoru

AU - Hasegawa, Daisuke

AU - Hatakeyama, Junji

AU - Hara, Naoki

AU - Higashibeppu, Naoki

AU - Furushima, Nana

AU - Furusono, Hirotaka

AU - Matsuishi, Yujiro

AU - Matsuyama, Tasuku

AU - Minematsu, Yusuke

AU - Miyashita, Ryoichi

AU - Miyatake, Yuji

AU - Moriyasu, Megumi

AU - Yamada, Toru

AU - Yamada, Hiroyuki

AU - Yamamoto, Ryo

AU - Yoshida, Takeshi

AU - Yoshida, Yuhei

AU - Yoshimura, Jumpei

AU - Yotsumoto, Ryuichi

AU - Yonekura, Hiroshi

AU - Wada, Takeshi

AU - Watanabe, Eizo

AU - Aoki, Makoto

AU - Asai, Hideki

AU - Abe, Takakuni

AU - Igarashi, Yutaka

AU - Iguchi, Naoya

AU - Ishikawa, Masami

AU - Ishimaru, Go

AU - Isokawa, Shutaro

AU - Itakura, Ryuta

AU - Imahase, Hisashi

AU - Imura, Haruki

AU - Irinoda, Takashi

AU - Uehara, Kenji

AU - Ushio, Noritaka

AU - Umegaki, Takeshi

AU - Egawa, Yuko

AU - Enomoto, Yuki

AU - Ota, Kohei

AU - Ohchi, Yoshifumi

AU - Ohno, Takanori

AU - Ohbe, Hiroyuki

AU - Oka, Kazuyuki

AU - Okada, Nobunaga

AU - Okada, Yohei

AU - Okano, Hiromu

AU - Okamoto, Jun

AU - Okuda, Hiroshi

AU - Ogura, Takayuki

AU - Onodera, Yu

AU - Oyama, Yuhta

AU - Kainuma, Motoshi

AU - Kako, Eisuke

AU - Kashiura, Masahiro

AU - Kato, Hiromi

AU - Kanaya, Akihiro

AU - Kaneko, Tadashi

AU - Kanehata, Keita

AU - Kano, Ken ichi

AU - Kawano, Hiroyuki

AU - Kikutani, Kazuya

AU - Kikuchi, Hitoshi

AU - Kido, Takahiro

AU - Kimura, Sho

AU - Koami, Hiroyuki

AU - Kobashi, Daisuke

AU - Saiki, Iwao

AU - Sakai, Masahito

AU - Sakamoto, Ayaka

AU - Sato, Tetsuya

AU - Shiga, Yasuhiro

AU - Shimoto, Manabu

AU - Shimoyama, Shinya

AU - Shoko, Tomohisa

AU - Sugawara, Yoh

AU - Sugita, Atsunori

AU - Suzuki, Satoshi

AU - Suzuki, Yuji

AU - Suhara, Tomohiro

AU - Sonota, Kenji

AU - Takauji, Shuhei

AU - Takashima, Kohei

AU - Takahashi, Sho

AU - Takahashi, Yoko

AU - Takeshita, Jun

AU - Tanaka, Yuuki

AU - Tampo, Akihito

AU - Tsunoyama, Taichiro

AU - Tetsuhara, Kenichi

AU - Tokunaga, Kentaro

AU - Tomioka, Yoshihiro

AU - Tomita, Kentaro

AU - Tominaga, Naoki

AU - Toyosaki, Mitsunobu

AU - Toyoda, Yukitoshi

AU - Naito, Hiromichi

AU - Nagata, Isao

AU - Nagato, Tadashi

AU - Nakamura, Yoshimi

AU - Nakamori, Yuki

AU - Nahara, Isao

AU - Naraba, Hiromu

AU - Narita, Chihiro

AU - Nishioka, Norihiro

AU - Nishimura, Tomoya

AU - Nishiyama, Kei

AU - Nomura, Tomohisa

AU - Haga, Taiki

AU - Hagiwara, Yoshihiro

AU - Hashimoto, Katsuhiko

AU - Hatachi, Takeshi

AU - Hamasaki, Toshiaki

AU - Hayashi, Takuya

AU - Hayashi, Minoru

AU - Hayamizu, Atsuki

AU - Haraguchi, Go

AU - Hirano, Yohei

AU - Fujii, Ryo

AU - Fujita, Motoki

AU - Fujimura, Naoyuki

AU - Funakoshi, Hiraku

AU - Horiguchi, Masahito

AU - Maki, Jun

AU - Masunaga, Naohisa

AU - Matsumura, Yosuke

AU - Mayumi, Takuya

AU - Minami, Keisuke

AU - Miyazaki, Yuya

AU - Miyamoto, Kazuyuki

AU - Murata, Teppei

AU - Yanai, Machi

AU - Yano, Takao

AU - Yamada, Kohei

AU - Yamada, Naoki

AU - Yamamoto, Tomonori

AU - Yoshihiro, Shodai

AU - Tanaka, Hiroshi

AU - Nishida, Osamu

N1 - Funding Information: These guidelines were prepared with financial support from the Japan Society of Intensive Care Medicine and the Japanese Association for Acute Medicine. No member of the Guideline Creation Committee received any form of financial compensation during the preparation of these guidelines. The views and interests of these societies were not reflected in the preparation of the guidelines’ recommendations. Funding Information: We would like to thank Minds for their guidance and support to create these guidelines, and Editage (www.editage.jp) for their English language editing service. We also gratefully acknowledge Dr. Masaaki Sakuraya for his contribution to the English version of J-SSCG2020 as the creation leader of the academic guideline promotion members, and Ms. Yumika Yoshida in the Japanese Society of Intensive Care Medicine Secretariat and Mr. Shuta Fukuda in the Japanese Association for Acute Medicine Secretariat for their kind supports. Publisher Copyright: © 2021, The Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/12

Y1 - 2021/12

N2 - The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created as revised from J-SSCG 2016 jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in September 2020 and published in February 2021. An English-language version of these guidelines was created based on the contents of the original Japanese-language version. The purpose of this guideline is to assist medical staff in making appropriate decisions to improve the prognosis of patients undergoing treatment for sepsis and septic shock. We aimed to provide high-quality guidelines that are easy to use and understand for specialists, general clinicians, and multidisciplinary medical professionals. J-SSCG 2016 took up new subjects that were not present in SSCG 2016 (e.g., ICU-acquired weakness [ICU-AW], post-intensive care syndrome [PICS], and body temperature management). The J-SSCG 2020 covered a total of 22 areas with four additional new areas (patient- and family-centered care, sepsis treatment system, neuro-intensive treatment, and stress ulcers). A total of 118 important clinical issues (clinical questions, CQs) were extracted regardless of the presence or absence of evidence. These CQs also include those that have been given particular focus within Japan. This is a large-scale guideline covering multiple fields; thus, in addition to the 25 committee members, we had the participation and support of a total of 226 members who are professionals (physicians, nurses, physiotherapists, clinical engineers, and pharmacists) and medical workers with a history of sepsis or critical illness. The GRADE method was adopted for making recommendations, and the modified Delphi method was used to determine recommendations by voting from all committee members. As a result, 79 GRADE-based recommendations, 5 Good Practice Statements (GPS), 18 expert consensuses, 27 answers to background questions (BQs), and summaries of definitions and diagnosis of sepsis were created as responses to 118 CQs. We also incorporated visual information for each CQ according to the time course of treatment, and we will also distribute this as an app. The J-SSCG 2020 is expected to be widely used as a useful bedside guideline in the field of sepsis treatment both in Japan and overseas involving multiple disciplines.

AB - The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created as revised from J-SSCG 2016 jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in September 2020 and published in February 2021. An English-language version of these guidelines was created based on the contents of the original Japanese-language version. The purpose of this guideline is to assist medical staff in making appropriate decisions to improve the prognosis of patients undergoing treatment for sepsis and septic shock. We aimed to provide high-quality guidelines that are easy to use and understand for specialists, general clinicians, and multidisciplinary medical professionals. J-SSCG 2016 took up new subjects that were not present in SSCG 2016 (e.g., ICU-acquired weakness [ICU-AW], post-intensive care syndrome [PICS], and body temperature management). The J-SSCG 2020 covered a total of 22 areas with four additional new areas (patient- and family-centered care, sepsis treatment system, neuro-intensive treatment, and stress ulcers). A total of 118 important clinical issues (clinical questions, CQs) were extracted regardless of the presence or absence of evidence. These CQs also include those that have been given particular focus within Japan. This is a large-scale guideline covering multiple fields; thus, in addition to the 25 committee members, we had the participation and support of a total of 226 members who are professionals (physicians, nurses, physiotherapists, clinical engineers, and pharmacists) and medical workers with a history of sepsis or critical illness. The GRADE method was adopted for making recommendations, and the modified Delphi method was used to determine recommendations by voting from all committee members. As a result, 79 GRADE-based recommendations, 5 Good Practice Statements (GPS), 18 expert consensuses, 27 answers to background questions (BQs), and summaries of definitions and diagnosis of sepsis were created as responses to 118 CQs. We also incorporated visual information for each CQ according to the time course of treatment, and we will also distribute this as an app. The J-SSCG 2020 is expected to be widely used as a useful bedside guideline in the field of sepsis treatment both in Japan and overseas involving multiple disciplines.

KW - Evidence-based medicine

KW - GRADE

KW - Guidelines

KW - Sepsis

KW - Septic shock

KW - Systematic review

UR - http://www.scopus.com/inward/record.url?scp=85113378700&partnerID=8YFLogxK

U2 - 10.1186/s40560-021-00555-7

DO - 10.1186/s40560-021-00555-7

M3 - Article

C2 - 34484801

AN - SCOPUS:85113378700

VL - 9

JO - Journal of Intensive Care

JF - Journal of Intensive Care

SN - 2052-0492

IS - 1

M1 - 53

ER -

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

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