The ins and outs of the transmembrane 4 superfamily

Mark D. Wright; Michael G. Tomlinson

doi:10.1016/0167-5699(94)90222-4

The ins and outs of the transmembrane 4 superfamily

Mark D. Wright, Michael G. Tomlinson

Research output: Contribution to journal › Article › Research › peer-review

340 Citations (Scopus)

Abstract

The recently discovered transmembrane 4 superfamily comprises a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains, which are presumed to be membrane spanning. At least seven of these molecules are expressed on leukocytes, and it seems likely that they mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.

Original language	English
Pages (from-to)	588-594
Number of pages	7
Journal	Immunology Today
Volume	15
Issue number	12
DOIs	https://doi.org/10.1016/0167-5699(94)90222-4
Publication status	Published - 1 Jan 1994
Externally published	Yes

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abstract = "The recently discovered transmembrane 4 superfamily comprises a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains, which are presumed to be membrane spanning. At least seven of these molecules are expressed on leukocytes, and it seems likely that they mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.",

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The ins and outs of the transmembrane 4 superfamily

Abstract

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