The incidence of Clostridioides difficile and Clostridium perfringens netF-positive strains in diarrheic dogs

Amanda Nadia Diniz, Fernanda Morcatti Coura, Maja Rupnik, Vicki Adams, Thomas L. Stent, Julian I. Rood, Carlos Augusto de Oliveira, Francisco Carlos Faria Lobato, Rodrigo Otávio Silveira Silva

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14 Citations (Scopus)


The aim of this study was to examine the incidence of Clostridioides (previously Clostridium) difficile and Clostridium perfringens in the feces of diarrheic and non-diarrheic dogs. Also, the presence of other common canine enteropathogens was examined. Toxigenic C. difficile and C. perfringens positive for the NetF-encoding gene (netF) were detected in 11 (11.9%) and seven (7.6%) diarrheic dogs, respectively. Three dogs were diagnosed simultaneously with toxigenic C. difficile and netF-positive C. perfringens. Among other enteropathogens, Giardia sp. was the most common agent detected in dogs positive for toxigenic C. difficile or netF-positive C. perfringens. The results suggest that C. difficile and C. perfringens occur more frequently as a primary cause of diarrhea.

Original languageEnglish
Pages (from-to)58-62
Number of pages5
Publication statusPublished - 1 Feb 2018


  • Canine diarrhea
  • Clostridioides difficile
  • Clostridium perfringens
  • Enteric pathogens
  • NetF

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