The impact of gynaecological cancer treatment on physical activity levels

a systematic review of observational studies

Kuan Yin Lin, Lara Edbrooke, Catherine L. Granger, Linda Denehy, Helena C. Frawley

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

Abstract

Background: The natural history of physical activity levels during and following gynaecological cancer treatment is not well understood. This is required in order to establish the time at which physical activity levels are lowest in order to target cancer rehabilitation or exercise interventions in gynaecological cancer population accordingly. Objectives: To conduct a systematic review to evaluate the impact of gynaecological cancer treatments on physical activity levels and to summarise the pattern of changes in physical activity levels over time among patients with gynaecological cancer. Methods: A comprehensive literature search was performed via MEDLINE (1946–2018), CINAHL (1982–2018), EMBASE (1947–2018), Ovid Emcare (1947–2018), PsycINFO (1806–2018) and the Cochrane Library (1991–2018). Studies were eligible for inclusion if they had assessed changes in physical activity levels during and after gynaecological cancer treatment. The methodological quality of the eligible studies was assessed by two independent reviewers using the Joanna Briggs Institute Critical Appraisal Tools. Results: In total, six studies (three cohort studies and three cross-sectional studies) with 1607 participants were included. All studies used patient-reported physical activity measures. Two of the three cohort studies measured patient-recalled physical activity levels before diagnosis (baseline), and length of follow-up varied across all studies. The majority of participants were treated surgically ± adjuvant therapy. Physical activity levels decreased at 6 months following surgery when compared with pre-treatment levels. Approximately 91% of participants did not meet physical activity guidelines 2 years following diagnosis, and 58% reported being less physically active 3 years after diagnosis, compared with the pre-diagnosis levels. Conclusions: Despite the paucity of evidence and limitations in the current body of literature, this review demonstrated that compared to pre-diagnosis, levels of physical activity remain low in gynaecological cancer survivors up to 3 years after diagnosis. More research is warranted to better characterise the pattern of change of physical activity levels across the disease trajectory and identify changes in physical activity patterns by cancer treatments and gynaecological tumour streams in order to target interventions accordingly.

Original languageEnglish
Pages (from-to)79-92
Number of pages14
JournalBrazilian Journal of Physical Therapy
Volume23
Issue number2
DOIs
Publication statusPublished - Mar 2019

Keywords

  • Gynaecological cancer
  • Ovarian cancer
  • Physical activity
  • Physical therapy
  • Rehabilitation
  • Systematic review

Cite this

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title = "The impact of gynaecological cancer treatment on physical activity levels: a systematic review of observational studies",
abstract = "Background: The natural history of physical activity levels during and following gynaecological cancer treatment is not well understood. This is required in order to establish the time at which physical activity levels are lowest in order to target cancer rehabilitation or exercise interventions in gynaecological cancer population accordingly. Objectives: To conduct a systematic review to evaluate the impact of gynaecological cancer treatments on physical activity levels and to summarise the pattern of changes in physical activity levels over time among patients with gynaecological cancer. Methods: A comprehensive literature search was performed via MEDLINE (1946–2018), CINAHL (1982–2018), EMBASE (1947–2018), Ovid Emcare (1947–2018), PsycINFO (1806–2018) and the Cochrane Library (1991–2018). Studies were eligible for inclusion if they had assessed changes in physical activity levels during and after gynaecological cancer treatment. The methodological quality of the eligible studies was assessed by two independent reviewers using the Joanna Briggs Institute Critical Appraisal Tools. Results: In total, six studies (three cohort studies and three cross-sectional studies) with 1607 participants were included. All studies used patient-reported physical activity measures. Two of the three cohort studies measured patient-recalled physical activity levels before diagnosis (baseline), and length of follow-up varied across all studies. The majority of participants were treated surgically ± adjuvant therapy. Physical activity levels decreased at 6 months following surgery when compared with pre-treatment levels. Approximately 91{\%} of participants did not meet physical activity guidelines 2 years following diagnosis, and 58{\%} reported being less physically active 3 years after diagnosis, compared with the pre-diagnosis levels. Conclusions: Despite the paucity of evidence and limitations in the current body of literature, this review demonstrated that compared to pre-diagnosis, levels of physical activity remain low in gynaecological cancer survivors up to 3 years after diagnosis. More research is warranted to better characterise the pattern of change of physical activity levels across the disease trajectory and identify changes in physical activity patterns by cancer treatments and gynaecological tumour streams in order to target interventions accordingly.",
keywords = "Gynaecological cancer, Ovarian cancer, Physical activity, Physical therapy, Rehabilitation, Systematic review",
author = "Lin, {Kuan Yin} and Lara Edbrooke and Granger, {Catherine L.} and Linda Denehy and Frawley, {Helena C.}",
year = "2019",
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The impact of gynaecological cancer treatment on physical activity levels : a systematic review of observational studies. / Lin, Kuan Yin; Edbrooke, Lara; Granger, Catherine L.; Denehy, Linda; Frawley, Helena C.

In: Brazilian Journal of Physical Therapy, Vol. 23, No. 2, 03.2019, p. 79-92.

Research output: Contribution to journalReview ArticleResearchpeer-review

TY - JOUR

T1 - The impact of gynaecological cancer treatment on physical activity levels

T2 - a systematic review of observational studies

AU - Lin, Kuan Yin

AU - Edbrooke, Lara

AU - Granger, Catherine L.

AU - Denehy, Linda

AU - Frawley, Helena C.

PY - 2019/3

Y1 - 2019/3

N2 - Background: The natural history of physical activity levels during and following gynaecological cancer treatment is not well understood. This is required in order to establish the time at which physical activity levels are lowest in order to target cancer rehabilitation or exercise interventions in gynaecological cancer population accordingly. Objectives: To conduct a systematic review to evaluate the impact of gynaecological cancer treatments on physical activity levels and to summarise the pattern of changes in physical activity levels over time among patients with gynaecological cancer. Methods: A comprehensive literature search was performed via MEDLINE (1946–2018), CINAHL (1982–2018), EMBASE (1947–2018), Ovid Emcare (1947–2018), PsycINFO (1806–2018) and the Cochrane Library (1991–2018). Studies were eligible for inclusion if they had assessed changes in physical activity levels during and after gynaecological cancer treatment. The methodological quality of the eligible studies was assessed by two independent reviewers using the Joanna Briggs Institute Critical Appraisal Tools. Results: In total, six studies (three cohort studies and three cross-sectional studies) with 1607 participants were included. All studies used patient-reported physical activity measures. Two of the three cohort studies measured patient-recalled physical activity levels before diagnosis (baseline), and length of follow-up varied across all studies. The majority of participants were treated surgically ± adjuvant therapy. Physical activity levels decreased at 6 months following surgery when compared with pre-treatment levels. Approximately 91% of participants did not meet physical activity guidelines 2 years following diagnosis, and 58% reported being less physically active 3 years after diagnosis, compared with the pre-diagnosis levels. Conclusions: Despite the paucity of evidence and limitations in the current body of literature, this review demonstrated that compared to pre-diagnosis, levels of physical activity remain low in gynaecological cancer survivors up to 3 years after diagnosis. More research is warranted to better characterise the pattern of change of physical activity levels across the disease trajectory and identify changes in physical activity patterns by cancer treatments and gynaecological tumour streams in order to target interventions accordingly.

AB - Background: The natural history of physical activity levels during and following gynaecological cancer treatment is not well understood. This is required in order to establish the time at which physical activity levels are lowest in order to target cancer rehabilitation or exercise interventions in gynaecological cancer population accordingly. Objectives: To conduct a systematic review to evaluate the impact of gynaecological cancer treatments on physical activity levels and to summarise the pattern of changes in physical activity levels over time among patients with gynaecological cancer. Methods: A comprehensive literature search was performed via MEDLINE (1946–2018), CINAHL (1982–2018), EMBASE (1947–2018), Ovid Emcare (1947–2018), PsycINFO (1806–2018) and the Cochrane Library (1991–2018). Studies were eligible for inclusion if they had assessed changes in physical activity levels during and after gynaecological cancer treatment. The methodological quality of the eligible studies was assessed by two independent reviewers using the Joanna Briggs Institute Critical Appraisal Tools. Results: In total, six studies (three cohort studies and three cross-sectional studies) with 1607 participants were included. All studies used patient-reported physical activity measures. Two of the three cohort studies measured patient-recalled physical activity levels before diagnosis (baseline), and length of follow-up varied across all studies. The majority of participants were treated surgically ± adjuvant therapy. Physical activity levels decreased at 6 months following surgery when compared with pre-treatment levels. Approximately 91% of participants did not meet physical activity guidelines 2 years following diagnosis, and 58% reported being less physically active 3 years after diagnosis, compared with the pre-diagnosis levels. Conclusions: Despite the paucity of evidence and limitations in the current body of literature, this review demonstrated that compared to pre-diagnosis, levels of physical activity remain low in gynaecological cancer survivors up to 3 years after diagnosis. More research is warranted to better characterise the pattern of change of physical activity levels across the disease trajectory and identify changes in physical activity patterns by cancer treatments and gynaecological tumour streams in order to target interventions accordingly.

KW - Gynaecological cancer

KW - Ovarian cancer

KW - Physical activity

KW - Physical therapy

KW - Rehabilitation

KW - Systematic review

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M3 - Review Article

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JF - Brazilian Journal of Physical Therapy

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