Abstract
A lack of physical activity is linked to the development of many chronic diseases. It is now well established that the immune system and inflammation play a central role in the development of numerous chronic metabolic diseases including insulin resistance, type 2 diabetes, atherosclerosis, nonalcoholic fatty liver disease, and specific types of cancer. Physical exercise elicits potent anti-inflammatory effects that are likely to account for many of the salutary actions of regular exercise on chronic metabolic diseases. Here we review the anti-inflammatory and immunomodulatory mechanisms by which the beneficial effects of exercise on chronic metabolic diseases may be mediated.
| Original language | English |
|---|---|
| Pages (from-to) | 262-269 |
| Number of pages | 8 |
| Journal | Trends in Immunology |
| Volume | 35 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2014 |
| Externally published | Yes |
Keywords
- Anti-inflammatory
- Exercise
- Immune cells
- Inflammation
- Metabolic disease
- Muscle