The immune response to influenza a viruses

Justine D. Mintern, Carole Guillonneau, Stephen J. Turner, Peter C Doherty

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

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The influenza A viruses are dangerous pathogens with the potential to provoke devastating disease. The challenge for the medical research community is to design preventive measures and therapeutic interventions that will limit the severe consequences of pandemic influenza A virus infections. Vaccines have long been available, but there is considerable scope for improvement as they target only the prevailing influenza A virus strains, do not give broad immunity, and work poorly in the elderly, the target group that is most at risk of fatal disease. Improved vaccines will only emerge if the development strategy is based on a firm understanding of the host immune response to the virus. Here, we summarize the research to date that details immune mechanisms participating in the control and elimination of influenza A viruses.

Original languageEnglish
Title of host publicationInfluenza Vaccines for the Future
EditorsRino Rappuoli, Giuseppe Del Giudice
Place of PublicationBasel Switzerland
Number of pages25
ISBN (Electronic)9783034602792
ISBN (Print)9783034602785
Publication statusPublished - 2011
Externally publishedYes

Publication series

NameBirkhauser Advances in Infectious Diseases

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