The Human Kidney: Parallels in Structure, Spatial Development, and Timing of Nephrogenesis

Luise A Cullen-McEwen; Megan R Sutherland; M Jane Black

doi:10.1016/B978-0-12-800102-8.00003-5

The Human Kidney: Parallels in Structure, Spatial Development, and Timing of Nephrogenesis

Luise A Cullen-McEwen, Megan R Sutherland, M Jane Black

Anatomy & Developmental Biology

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

29 Citations (Scopus)

Abstract

Over the recent decades there has been extensive investigation into the genetic/molecular regulation and cellular/molecular mechanisms of nephrogenesis and ultimate kidney development in animal models, but to date these have not been examined in the human kidney. This chapter highlights the differences in the anatomic structure and spatial and temporal ontogeny of the kidney in animal models compared to humans. In doing so, it emphasizes that caution needs to be taken when extrapolating findings from animal models to humans.

Original language	English
Title of host publication	Kidney Development, Disease, Repair and Regeneration
Editors	M Little
Place of Publication	UK
Publisher	Academic Press
Pages	27-40
Number of pages	14
Edition	1st
ISBN (Electronic)	9780128004388
ISBN (Print)	9780128001028
DOIs	https://doi.org/10.1016/B978-0-12-800102-8.00003-5
Publication status	Published - 2016

Keywords

Arcades
Branching morphogenesis
Nephrogenesis
Nephron endowment
Papillae

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10.1016/B978-0-12-800102-8.00003-5

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The Human Kidney: Parallels in Structure, Spatial Development, and Timing of Nephrogenesis. / Cullen-McEwen, Luise A; Sutherland, Megan R; Black, M Jane.
Kidney Development, Disease, Repair and Regeneration. ed. / M Little. 1st. ed. UK: Academic Press, 2016. p. 27-40.

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

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The Human Kidney: Parallels in Structure, Spatial Development, and Timing of Nephrogenesis

Abstract

Keywords

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