Over the recent decades there has been extensive investigation into the genetic/molecular regulation and cellular/molecular mechanisms of nephrogenesis and ultimate kidney development in animal models, but to date these have not been examined in the human kidney. This chapter highlights the differences in the anatomic structure and spatial and temporal ontogeny of the kidney in animal models compared to humans. In doing so, it emphasizes that caution needs to be taken when extrapolating findings from animal models to humans.
|Title of host publication||Kidney Development, Disease, Repair and Regeneration|
|Place of Publication||UK|
|Number of pages||14|
|Publication status||Published - 2016|
- Branching morphogenesis
- Nephron endowment