The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix

Ruby H P Law; James Alexander Irving; Ashley Maurice Buckle; Katya Ruzyla; Marguerite Stella Buzza; Tanya Ann Bashtannyk-Puhalovich; Travis Clarke Beddoe; Kim-Ngoc Nguyen; Margaret D Worrall; Stephen Paul Bottomley; Phillip Ian Bird; Jamie Rossjohn; James C Whisstock

doi:10.1074/jbc.M412043200

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix

Ruby H P Law, James Alexander Irving, Ashley Maurice Buckle, Katya Ruzyla, Marguerite Stella Buzza, Tanya Ann Bashtannyk-Puhalovich, Travis Clarke Beddoe, Kim-Ngoc Nguyen, Margaret D Worrall, Stephen Paul Bottomley, Phillip Ian Bird, Jamie Rossjohn, James C Whisstock

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › Research › peer-review

60 Citations (Scopus)

Original language	English
Pages (from-to)	22356 - 22364
Number of pages	9
Journal	Journal of Biological Chemistry
Volume	280
Issue number	23
DOIs	https://doi.org/10.1074/jbc.M412043200
Publication status	Published - 2005

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10.1074/jbc.M412043200

Cite this

Law, R. H. P., Irving, J. A., Buckle, A. M., Ruzyla, K., Buzza, M. S., Bashtannyk-Puhalovich, T. A., Beddoe, T. C., Nguyen, K-N., Worrall, M. D., Bottomley, S. P., Bird, P. I., Rossjohn, J., & Whisstock, J. C. (2005). The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. Journal of Biological Chemistry, 280(23), 22356 - 22364. https://doi.org/10.1074/jbc.M412043200

Law, Ruby H P ; Irving, James Alexander ; Buckle, Ashley Maurice ; Ruzyla, Katya ; Buzza, Marguerite Stella ; Bashtannyk-Puhalovich, Tanya Ann ; Beddoe, Travis Clarke ; Nguyen, Kim-Ngoc ; Worrall, Margaret D ; Bottomley, Stephen Paul ; Bird, Phillip Ian ; Rossjohn, Jamie ; Whisstock, James C. / The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. In: Journal of Biological Chemistry. 2005 ; Vol. 280, No. 23. pp. 22356 - 22364.

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title = "The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix",

author = "Law, {Ruby H P} and Irving, {James Alexander} and Buckle, {Ashley Maurice} and Katya Ruzyla and Buzza, {Marguerite Stella} and Bashtannyk-Puhalovich, {Tanya Ann} and Beddoe, {Travis Clarke} and Kim-Ngoc Nguyen and Worrall, {Margaret D} and Bottomley, {Stephen Paul} and Bird, {Phillip Ian} and Jamie Rossjohn and Whisstock, {James C}",

year = "2005",

doi = "10.1074/jbc.M412043200",

language = "English",

volume = "280",

pages = "22356 -- 22364",

journal = "Journal of Biological Chemistry",

issn = "1083-351X",

publisher = "American Society for Biochemistry and Molecular Biology",

number = "23",

}

Law, RHP, Irving, JA, Buckle, AM, Ruzyla, K, Buzza, MS, Bashtannyk-Puhalovich, TA, Beddoe, TC, Nguyen, K-N, Worrall, MD, Bottomley, SP, Bird, PI , Rossjohn, J & Whisstock, JC 2005, 'The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix', Journal of Biological Chemistry, vol. 280, no. 23, pp. 22356 - 22364. https://doi.org/10.1074/jbc.M412043200

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. / Law, Ruby H P; Irving, James Alexander; Buckle, Ashley Maurice; Ruzyla, Katya; Buzza, Marguerite Stella; Bashtannyk-Puhalovich, Tanya Ann; Beddoe, Travis Clarke; Nguyen, Kim-Ngoc; Worrall, Margaret D; Bottomley, Stephen Paul; Bird, Phillip Ian ; Rossjohn, Jamie ; Whisstock, James C.

In: Journal of Biological Chemistry, Vol. 280, No. 23, 2005, p. 22356 - 22364.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix

AU - Law, Ruby H P

AU - Irving, James Alexander

AU - Buckle, Ashley Maurice

AU - Ruzyla, Katya

AU - Buzza, Marguerite Stella

AU - Bashtannyk-Puhalovich, Tanya Ann

AU - Beddoe, Travis Clarke

AU - Nguyen, Kim-Ngoc

AU - Worrall, Margaret D

AU - Bottomley, Stephen Paul

AU - Bird, Phillip Ian

AU - Rossjohn, Jamie

AU - Whisstock, James C

PY - 2005

Y1 - 2005

U2 - 10.1074/jbc.M412043200

DO - 10.1074/jbc.M412043200

M3 - Article

VL - 280

SP - 22356

EP - 22364

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 1083-351X

IS - 23

ER -