The Fitts task reveals impairments in planning and online control of movement in Friedreich Ataxia: Reduced cerebellar-cortico connectivity?

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Abstract

Friedreich ataxia (FRDA) is the most common of the inherited ataxias. We have suggested that people with FRDA may have impairment in cognitive and/or psychomotor capacity either due to disturbance of projections of the cerebellum to the cortex, direct cortical pathology or perhaps both. To further explore this possibility, we used a movement task incorporating Fitts Law, a robust description of the relationship between movement time and accuracy in goal-directed aiming movements.
Original languageEnglish
Pages (from-to)382 - 390
Number of pages9
JournalNeuroscience
Volume192
Publication statusPublished - 2011

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