The first practical asymmetric synthesis of R and S-warfarin

Andrea Robinson; Hui Yin Li; John Feaster

doi:10.1016/0040-4039(96)01796-0

The first practical asymmetric synthesis of R and S-warfarin

Andrea Robinson, Hui Yin Li, John Feaster

Research output: Contribution to journal › Article › Research › peer-review

48 Citations (Scopus)

Abstract

A highly efficient synthesis of both enantiomers of warfarin Ia and Ib has been developed by using a novel two step 'chiral switch' strategy and a DuPHOS-Rh(I) catalyzed asymmetric hydrogenation.

Original language	English
Pages (from-to)	8321-8324
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	46
DOIs	https://doi.org/10.1016/0040-4039(96)01796-0
Publication status	Published - 11 Nov 1996
Externally published	Yes

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title = "The first practical asymmetric synthesis of R and S-warfarin",

abstract = "A highly efficient synthesis of both enantiomers of warfarin Ia and Ib has been developed by using a novel two step 'chiral switch' strategy and a DuPHOS-Rh(I) catalyzed asymmetric hydrogenation.",

author = "Andrea Robinson and Li, {Hui Yin} and John Feaster",

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AU - Li, Hui Yin

AU - Feaster, John

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N2 - A highly efficient synthesis of both enantiomers of warfarin Ia and Ib has been developed by using a novel two step 'chiral switch' strategy and a DuPHOS-Rh(I) catalyzed asymmetric hydrogenation.

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DO - 10.1016/0040-4039(96)01796-0

M3 - Article

AN - SCOPUS:0030580374

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VL - 37

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EP - 8324

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 46

ER -

The first practical asymmetric synthesis of R and S-warfarin

Abstract

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