The first international consensus conference on continuous renal replacement therapy

John A. Kellum, Ravindra L. Mehta, Derek C. Angus, Paul Palevsky, Claudio Ronco, Rinaldo Bellomo, Timothy Bunchman, William Clark, Andrew Davenport, Thomas Depner, R. T.Noel Gibney, John A. Kellum, Paul Kimmel, J. Michael Lazarus, Martine Leblanc, Nathan Levin, Ravindra L. Mehta, Sangeeta Mehta, Patrick T. Murray, Emil P. PaganiniPaul Palevsky, Claudio Ronco, Miet Schetz, Robert A. Star, Ciro Tetta, David Wensley

Research output: Contribution to journalArticleOtherpeer-review

144 Citations (Scopus)

Abstract

Background. Management of acute renal failure (ARF) in the critically ill is extremely variable and there are no published standards for the provision of renal replacement therapy in this population. We sought to review the available evidence, make evidence-based practice recommendations, and delineate key questions for future study. Methods. We undertook an evidence-based review of the literature on continuous renal replacement therapy (CRRT) using MEDLINE searches. We determined a list of key questions and convened a 2-day consensus conference to develop summary statements via a series of alternatingbreakout and plenary sessions. In these sessions, we identified supporting evidence and generated practice guidelines and/or directions for future research. Results. Of the 46 questions considered, we found consensus for 20. We found inadequate evidence for 21 questions and for the remaining five we found data but no consensus. Full versions of workgroup findings are available on the Internet at www.ADQI.net. Conclusions. Despite limited data, broad areas of consensus exist for use of CRRT and guideline development appears feasible. Equally broad areas of disagreement also exist and additional basic and applied research in acute renal failure is needed.

Original languageEnglish
Pages (from-to)1855-1863
Number of pages9
JournalKidney International
Volume62
Issue number5
DOIs
Publication statusPublished - 1 Jan 2002
Externally publishedYes

Keywords

  • Acute renal failure
  • Continuous renal replacement therapy
  • Continuous venovenous hemofiltration
  • Hemodialysis

Cite this

Kellum, J. A., Mehta, R. L., Angus, D. C., Palevsky, P., Ronco, C., Bellomo, R., ... Wensley, D. (2002). The first international consensus conference on continuous renal replacement therapy. Kidney International, 62(5), 1855-1863. https://doi.org/10.1046/j.1523-1755.2002.00613.x
Kellum, John A. ; Mehta, Ravindra L. ; Angus, Derek C. ; Palevsky, Paul ; Ronco, Claudio ; Bellomo, Rinaldo ; Bunchman, Timothy ; Clark, William ; Davenport, Andrew ; Depner, Thomas ; Gibney, R. T.Noel ; Kellum, John A. ; Kimmel, Paul ; Lazarus, J. Michael ; Leblanc, Martine ; Levin, Nathan ; Mehta, Ravindra L. ; Mehta, Sangeeta ; Murray, Patrick T. ; Paganini, Emil P. ; Palevsky, Paul ; Ronco, Claudio ; Schetz, Miet ; Star, Robert A. ; Tetta, Ciro ; Wensley, David. / The first international consensus conference on continuous renal replacement therapy. In: Kidney International. 2002 ; Vol. 62, No. 5. pp. 1855-1863.
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keywords = "Acute renal failure, Continuous renal replacement therapy, Continuous venovenous hemofiltration, Hemodialysis",
author = "Kellum, {John A.} and Mehta, {Ravindra L.} and Angus, {Derek C.} and Paul Palevsky and Claudio Ronco and Rinaldo Bellomo and Timothy Bunchman and William Clark and Andrew Davenport and Thomas Depner and Gibney, {R. T.Noel} and Kellum, {John A.} and Paul Kimmel and Lazarus, {J. Michael} and Martine Leblanc and Nathan Levin and Mehta, {Ravindra L.} and Sangeeta Mehta and Murray, {Patrick T.} and Paganini, {Emil P.} and Paul Palevsky and Claudio Ronco and Miet Schetz and Star, {Robert A.} and Ciro Tetta and David Wensley",
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Kellum, JA, Mehta, RL, Angus, DC, Palevsky, P, Ronco, C, Bellomo, R, Bunchman, T, Clark, W, Davenport, A, Depner, T, Gibney, RTN, Kellum, JA, Kimmel, P, Lazarus, JM, Leblanc, M, Levin, N, Mehta, RL, Mehta, S, Murray, PT, Paganini, EP, Palevsky, P, Ronco, C, Schetz, M, Star, RA, Tetta, C & Wensley, D 2002, 'The first international consensus conference on continuous renal replacement therapy', Kidney International, vol. 62, no. 5, pp. 1855-1863. https://doi.org/10.1046/j.1523-1755.2002.00613.x

The first international consensus conference on continuous renal replacement therapy. / Kellum, John A.; Mehta, Ravindra L.; Angus, Derek C.; Palevsky, Paul; Ronco, Claudio; Bellomo, Rinaldo; Bunchman, Timothy; Clark, William; Davenport, Andrew; Depner, Thomas; Gibney, R. T.Noel; Kellum, John A.; Kimmel, Paul; Lazarus, J. Michael; Leblanc, Martine; Levin, Nathan; Mehta, Ravindra L.; Mehta, Sangeeta; Murray, Patrick T.; Paganini, Emil P.; Palevsky, Paul; Ronco, Claudio; Schetz, Miet; Star, Robert A.; Tetta, Ciro; Wensley, David.

In: Kidney International, Vol. 62, No. 5, 01.01.2002, p. 1855-1863.

Research output: Contribution to journalArticleOtherpeer-review

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T1 - The first international consensus conference on continuous renal replacement therapy

AU - Kellum, John A.

AU - Mehta, Ravindra L.

AU - Angus, Derek C.

AU - Palevsky, Paul

AU - Ronco, Claudio

AU - Bellomo, Rinaldo

AU - Bunchman, Timothy

AU - Clark, William

AU - Davenport, Andrew

AU - Depner, Thomas

AU - Gibney, R. T.Noel

AU - Kellum, John A.

AU - Kimmel, Paul

AU - Lazarus, J. Michael

AU - Leblanc, Martine

AU - Levin, Nathan

AU - Mehta, Ravindra L.

AU - Mehta, Sangeeta

AU - Murray, Patrick T.

AU - Paganini, Emil P.

AU - Palevsky, Paul

AU - Ronco, Claudio

AU - Schetz, Miet

AU - Star, Robert A.

AU - Tetta, Ciro

AU - Wensley, David

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Background. Management of acute renal failure (ARF) in the critically ill is extremely variable and there are no published standards for the provision of renal replacement therapy in this population. We sought to review the available evidence, make evidence-based practice recommendations, and delineate key questions for future study. Methods. We undertook an evidence-based review of the literature on continuous renal replacement therapy (CRRT) using MEDLINE searches. We determined a list of key questions and convened a 2-day consensus conference to develop summary statements via a series of alternatingbreakout and plenary sessions. In these sessions, we identified supporting evidence and generated practice guidelines and/or directions for future research. Results. Of the 46 questions considered, we found consensus for 20. We found inadequate evidence for 21 questions and for the remaining five we found data but no consensus. Full versions of workgroup findings are available on the Internet at www.ADQI.net. Conclusions. Despite limited data, broad areas of consensus exist for use of CRRT and guideline development appears feasible. Equally broad areas of disagreement also exist and additional basic and applied research in acute renal failure is needed.

AB - Background. Management of acute renal failure (ARF) in the critically ill is extremely variable and there are no published standards for the provision of renal replacement therapy in this population. We sought to review the available evidence, make evidence-based practice recommendations, and delineate key questions for future study. Methods. We undertook an evidence-based review of the literature on continuous renal replacement therapy (CRRT) using MEDLINE searches. We determined a list of key questions and convened a 2-day consensus conference to develop summary statements via a series of alternatingbreakout and plenary sessions. In these sessions, we identified supporting evidence and generated practice guidelines and/or directions for future research. Results. Of the 46 questions considered, we found consensus for 20. We found inadequate evidence for 21 questions and for the remaining five we found data but no consensus. Full versions of workgroup findings are available on the Internet at www.ADQI.net. Conclusions. Despite limited data, broad areas of consensus exist for use of CRRT and guideline development appears feasible. Equally broad areas of disagreement also exist and additional basic and applied research in acute renal failure is needed.

KW - Acute renal failure

KW - Continuous renal replacement therapy

KW - Continuous venovenous hemofiltration

KW - Hemodialysis

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