The First Cell Fate Decision During Mammalian Development

Melanie D White, Nicolas Plachta

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Abstract

Introduction During mammalian preimplantation development, the fertilized egg divides repeatedly to form seemingly identical totipotent blastomere cells, which are capable of producing any cell in the embryo or its supporting tissues. At some stage, these blastomeres relinquish their totipotency and assume different identities. How and when blastomeres first start down the pathway to adopting different fates remains an open question.
Original languageEnglish
Title of host publicationStem Cells, Tissue Engineering and Regenerative Medicine
EditorsDavid Warburton
Place of PublicationSingapore
PublisherWorld Scientific Publishing
Pages25-39
Number of pages15
Edition1st
ISBN (Print)9789814612777
DOIs
Publication statusPublished - 2015

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