The evolving world of pseudoenzymes: Proteins, prejudice and zombies

Patrick A. Eyers, James M. Murphy

Research output: Contribution to journalArticleResearchpeer-review

69 Citations (Scopus)

Abstract

Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs.

Original languageEnglish
Article number98
Number of pages6
JournalBMC Biology
Volume14
Issue number1
DOIs
Publication statusPublished - 11 Nov 2016
Externally publishedYes

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