TY - JOUR
T1 - The Evolving Facets of Bacterial Vaginosis
T2 - Implications for HIV Transmission
AU - McKinnon, Lyle R.
AU - Achilles, Sharon L.
AU - Bradshaw, Catriona S.
AU - Burgener, Adam
AU - Crucitti, Tania
AU - Fredricks, David N.
AU - Jaspan, Heather B.
AU - Kaul, Rupert
AU - Kaushic, Charu
AU - Klatt, Nichole
AU - Kwon, Douglas S.
AU - Marrazzo, Jeanne M.
AU - Masson, Lindi
AU - McClelland, R. Scott
AU - Ravel, Jacques
AU - van de Wijgert, Janneke H.H.M.
AU - Vodstrcil, Lenka A.
AU - Tachedjian, Gilda
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Bacterial vaginosis (BV) is a common yet poorly understood vaginal condition that has become a major focus of HIV transmission and immunology research. Varied terminologies are used by clinicians and researchers to describe microbial communities that reside in the female reproductive tract (FRT), which is driven, in part, by microbial genetic and metabolic complexity, evolving diagnostic and molecular techniques, and multidisciplinary perspectives of clinicians, epidemiologists, microbiologists, and immunologists who all appreciate the scientific importance of understanding mechanisms that underlie BV. This Perspectives article aims to clarify the varied terms used to describe the cervicovaginal microbiota and its "nonoptimal" state, under the overarching term of BV. The ultimate goal is to move toward language standardization in future literature that facilitates a better understanding of the impact of BV on FRT immunology and risk of sexually transmitted infections, including HIV.
AB - Bacterial vaginosis (BV) is a common yet poorly understood vaginal condition that has become a major focus of HIV transmission and immunology research. Varied terminologies are used by clinicians and researchers to describe microbial communities that reside in the female reproductive tract (FRT), which is driven, in part, by microbial genetic and metabolic complexity, evolving diagnostic and molecular techniques, and multidisciplinary perspectives of clinicians, epidemiologists, microbiologists, and immunologists who all appreciate the scientific importance of understanding mechanisms that underlie BV. This Perspectives article aims to clarify the varied terms used to describe the cervicovaginal microbiota and its "nonoptimal" state, under the overarching term of BV. The ultimate goal is to move toward language standardization in future literature that facilitates a better understanding of the impact of BV on FRT immunology and risk of sexually transmitted infections, including HIV.
KW - bacterial vaginosis
KW - female reproductive tract
KW - genital inflammation
KW - HIV
KW - HIV transmission
KW - vaginal microbiota
UR - http://www.scopus.com/inward/record.url?scp=85062412846&partnerID=8YFLogxK
U2 - 10.1089/AID.2018.0304
DO - 10.1089/AID.2018.0304
M3 - Article
C2 - 30638028
AN - SCOPUS:85062412846
SN - 0889-2229
VL - 35
SP - 219
EP - 228
JO - AIDS Research and Human Retroviruses
JF - AIDS Research and Human Retroviruses
IS - 3
ER -
