An observational study was conducted to describe the epidemiology of bacteriuria and candiduria in the intensive care unit (ICU), and the occurrence of blood stream infection (BSI) associated with ICU-acquired positive urine culture. Between 2006 and 2011, 444 episodes of either bacteriuria or candiduria defined by positive urine culture (microorganisms =105 c.f.u./ml) occurred in 406 patients. Three hundred and seventy-seven (85 ) were hospital-acquired including 221 which were ICU-acquired (6?4 ? 0?8 episodes/1000 ICU days). Escherichia coli was the most common bacteria of both community- and ICU-acquired bacteriuria/candiduria (49?2 and 29 , respectively). Candida spp. represented 55 (129/236) of pathogens responsible for ICU-acquired positive urine cultures. Patients with ICU-acquired candiduria had greater illness severity at ICU admission than those with ICU-acquired bacteriuria (APACHE III score 79 ? 25 vs. 66 ? 31, P = 0?0015). BSI associated with ICU-acquired positive urine culture occurred in 0?15/1000 ICU days and was more often due to Candida. In this study, Candida was the most common pathogen responsible for ICU-acquired positive urine cultures and illness severity was a risk factor for candiduria in the study population.
- Adolescent Adult Aged Bacteremia/epidemiology/microbiology Bacteria/classification/*isolation & purification Candida/*isolation & purification Candidemia/epidemiology/microbiology Critical Illness Female Humans Intensive Care Units Male Middle Aged Retrospective Studies Severity of Illness Index Urinary Tract Infections/complications/*epidemiology/*microbiology Urine/*microbiology Young Adult Bacteriuria candiduria critically ill patients positive urine culture urinary tract infections