The emerging importance of receptor kinetics in drug discovery: what goes (k)on must come (k)off

Research output: Contribution to conferenceAbstract

Abstract

The characterization of receptor binding kinetics of preclinical drug candidates is now becoming more readily appreciated as a key addition to the discovery process. Benefits of studying kinetics include increased understanding of prolonged duration of action, ability to differentiate between different pre-clinical candidates and in the understanding of differential in vivo efficacies. At present these effects are dependent on the suitability of a radioligand and therefore limits which receptors and molecules can be investigated.
Original languageEnglish
Number of pages1
Publication statusPublished - 2014
EventASCEPT-MPGPCR 2014 - Melbourne Convention and Exhibition Centre, Melbourne, Australia
Duration: 7 Dec 201411 Dec 2014
https://www.asceptasm.com/2014-annual-scientific-meeting/program-keynote-speakers/

Conference

ConferenceASCEPT-MPGPCR 2014
Abbreviated titleASCEPT-MPGPCR
CountryAustralia
CityMelbourne
Period7/12/1411/12/14
Internet address

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