The Emergence of Allosteric Modulators for G Protein-Coupled Receptors

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

4 Citations (Scopus)
Original languageEnglish
Title of host publicationGPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions
PublisherJohn Wiley & Sons
Pages61-87
Number of pages27
ISBN (Print)9780470307786
DOIs
Publication statusPublished - 15 Jul 2010

Keywords

  • Allosteric interactions at GPCRs, with profound perturbations in ligand binding and GPCR function
  • Allosteric modulator emergence - for G protein-coupled receptors
  • Allosteric theory and allosteric modulators and their properties

Cite this

Gregory, K. J., Valant, C., Simms, J., Sexton, P. M., & Christopoulos, A. (2010). The Emergence of Allosteric Modulators for G Protein-Coupled Receptors. In GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions (pp. 61-87). John Wiley & Sons. https://doi.org/10.1002/9780470627327.ch3
Gregory, Karen J. ; Valant, Celine ; Simms, John ; Sexton, Patrick M. ; Christopoulos, Arthur. / The Emergence of Allosteric Modulators for G Protein-Coupled Receptors. GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. John Wiley & Sons, 2010. pp. 61-87
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Gregory, KJ, Valant, C, Simms, J, Sexton, PM & Christopoulos, A 2010, The Emergence of Allosteric Modulators for G Protein-Coupled Receptors. in GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. John Wiley & Sons, pp. 61-87. https://doi.org/10.1002/9780470627327.ch3

The Emergence of Allosteric Modulators for G Protein-Coupled Receptors. / Gregory, Karen J.; Valant, Celine; Simms, John; Sexton, Patrick M.; Christopoulos, Arthur.

GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. John Wiley & Sons, 2010. p. 61-87.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

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T1 - The Emergence of Allosteric Modulators for G Protein-Coupled Receptors

AU - Gregory, Karen J.

AU - Valant, Celine

AU - Simms, John

AU - Sexton, Patrick M.

AU - Christopoulos, Arthur

PY - 2010/7/15

Y1 - 2010/7/15

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KW - Allosteric modulator emergence - for G protein-coupled receptors

KW - Allosteric theory and allosteric modulators and their properties

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BT - GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions

PB - John Wiley & Sons

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Gregory KJ, Valant C, Simms J, Sexton PM, Christopoulos A. The Emergence of Allosteric Modulators for G Protein-Coupled Receptors. In GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. John Wiley & Sons. 2010. p. 61-87 https://doi.org/10.1002/9780470627327.ch3