The eliminate hepatitis C (EC) experience study: baseline characteristics of a cohort of people who inject drugs in Melbourne, Australia

Jack Gunn, Daniel O'Keefe, Bridget Louise Draper, Filip Djordjevic, Kathleen Ryan, Phoebe Kerr, Imogen Elsum, Judy Gold, Chloe Layton, Kico Chan, Paul Dietze, Peter Higgs, Joseph Doyle, Mark A. Stoové, Margaret Hellard, Alisa Pedrana

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objectives Direct-acting antivirals provide an opportunity to eliminate hepatitis C virus (HCV) as a public health threat in Australia, yet barriers to care remain. In this study, we use baseline data from a longitudinal cohort of people who inject drugs to understand differences in participant characteristics and explore experiences of stigma, health service utilisation and health literacy between three care cascade groups. Design Cross-sectional. Setting Community and private primary healthcare services in Melbourne, Australia. Participants Participants completed baseline surveys between 19 September 2018 and 15 December 2020. We recruited 288 participants; the median age was 42 years (IQR: 37-49 years) and 198 (69%) were male. At baseline, 103 (36%) self-reported being € not engaged in testing', 127 (44%) had HCV RNA positivity but were € not engaged in treatment' and 58 (20%) were € engaged in HCV treatment'. Outcome measures Descriptive statistics were used to present the baseline demographics, health service utilisation and experiences of stigma data. We explored differences in these scales between participant demographics using χ 2 test or fisher's exact tests, and differences between health literacy scores using one-way analysis of variance tests. Results A majority were in regular contact with multiple health services, and most had previously been identified as at-risk of HCV. In the 12 months preceding baseline, 70% reported any experiences of stigma related to injecting drug use. Assessment of health literacy data identified gaps for those € not engaged in testing' and € not engaged in treatment' across two relevant domains: € ability to appraise health information' and € ability to actively engage with healthcare providers'. Conclusion In eliminate hepatitis C experience, lower HCV testing and treatment may be explained by experiences of stigmatisation or gaps in health literacy. Enhanced interventions targeting people who inject drugs to promote HCV care are needed.

Original languageEnglish
Article numbere071665
Number of pages9
JournalBMJ Open
Volume13
Issue number7
DOIs
Publication statusPublished - 3 Jul 2023

Keywords

  • Health policy
  • Health Services Accessibility
  • Public health

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