The effects of radiofrequency electromagnetic radiation on sperm function

B. J. Houston, Brett Nixon, B. V. King, Geoffry N De Iuliis, R. J. Aitken

Research output: Contribution to journalReview ArticleResearchpeer-review

23 Citations (Scopus)

Abstract

Mobile phone usage has become an integral part of our lives. However, the effects of the radiofrequency electromagnetic radiation (RF-EMR) emitted by these devices on biological systems and specifically the reproductive systems are currently under active debate. A fundamental hindrance to the current debate is that there is no clear mechanism of how such non-ionising radiation influences biological systems. Therefore, we explored the documented impacts of RF-EMR on the male reproductive system and considered any common observations that could provide insights on a potential mechanism. Among a total of 27 studies investigating the effects of RF-EMR on the male reproductive system, negative consequences of exposure were reported in 21. Within these 21 studies, 11 of the 15 that investigated sperm motility reported significant declines, 7 of 7 that measured the production of reactive oxygen species (ROS) documented elevated levels and 4 of 5 studies that probed for DNA damage highlighted increased damage due to RF-EMR exposure. Associated with this, RF-EMR treatment reduced the antioxidant levels in 6 of 6 studies that discussed this phenomenon, whereas consequences of RF-EMR were successfully ameliorated with the supplementation of antioxidants in all 3 studies that carried out these experiments. In light of this, we envisage a two-step mechanism whereby RF-EMR is able to induce mitochondrial dysfunction leading to elevated ROS production. A continued focus on research, which aims to shed light on the biological effects of RF-EMR will allow us to test and assess this proposed mechanism in a variety of cell types.

Original languageEnglish
Pages (from-to)R263-R276
Number of pages14
JournalReproduction
Volume152
Issue number6
DOIs
Publication statusPublished - Dec 2016
Externally publishedYes

Cite this

Houston, B. J., Nixon, B., King, B. V., De Iuliis, G. N., & Aitken, R. J. (2016). The effects of radiofrequency electromagnetic radiation on sperm function. Reproduction, 152(6), R263-R276. https://doi.org/10.1530/REP-16-0126