The effects of dummy/pacifier use on infant blood pressure and autonomic activity during sleep

Stephanie Yiallourou, Hannah Poole, Pallavi Prathivadi, Alexsandria Odoi, Flora Yuen-Wait Wong, Rosemary Sylvia Claire Horne

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Dummy/pacifier use is protective for sudden infant death syndrome (SIDS); however, the mechanism/s for this are unknown. As impaired cardiovascular control may be the underlying cause of SIDS, we assessed the effects of dummy/pacifier use on cardiovascular control during sleep within the first 6 months of life. METHODS: Term infants, divided into dummy/pacifier users and non-dummy/pacifier users, were studied at 2-4 weeks (n = 27), 2-3 months (n = 35) and 5-6 months (n = 31) using daytime polysomnography. Heart rate, blood pressure (BP), heart rate variability (HRV), blood pressure variability (BPV), and baroreflex sensitivity (BRS) were measured in triplicate 1-2-min epochs during quiet and active sleep in the supine and prone positions. RESULTS: Overall, during the non-sucking periods, in the prone position, the BP was higher (10-22 mmHg) in dummy/pacifier users compared to non-users at 2-4 weeks and 5-6 months (p <0.05 for both). HRV and BRS were higher in dummy/pacifier users compared to non-users at 2-4 weeks (p <0.05). Active sucking increased HRV and BPV, consistent with increased sympathetic activity in dummy/pacifier users. CONCLUSIONS: Higher BP and HRV in dummy/pacifier users indicate increased sympathetic tone, which may serve as a protective mechanism against possible hypotension leading to SIDS; however, these effects were not apparent at 2-3 months, when the risk of SIDS is highest.
Original languageEnglish
Pages (from-to)1508 - 1516
Number of pages9
JournalSleep Medicine
Volume15
Issue number12
DOIs
Publication statusPublished - 2014

Cite this

@article{97c2e48b62fc4821bf7bd7fd759b1f67,
title = "The effects of dummy/pacifier use on infant blood pressure and autonomic activity during sleep",
abstract = "Dummy/pacifier use is protective for sudden infant death syndrome (SIDS); however, the mechanism/s for this are unknown. As impaired cardiovascular control may be the underlying cause of SIDS, we assessed the effects of dummy/pacifier use on cardiovascular control during sleep within the first 6 months of life. METHODS: Term infants, divided into dummy/pacifier users and non-dummy/pacifier users, were studied at 2-4 weeks (n = 27), 2-3 months (n = 35) and 5-6 months (n = 31) using daytime polysomnography. Heart rate, blood pressure (BP), heart rate variability (HRV), blood pressure variability (BPV), and baroreflex sensitivity (BRS) were measured in triplicate 1-2-min epochs during quiet and active sleep in the supine and prone positions. RESULTS: Overall, during the non-sucking periods, in the prone position, the BP was higher (10-22 mmHg) in dummy/pacifier users compared to non-users at 2-4 weeks and 5-6 months (p <0.05 for both). HRV and BRS were higher in dummy/pacifier users compared to non-users at 2-4 weeks (p <0.05). Active sucking increased HRV and BPV, consistent with increased sympathetic activity in dummy/pacifier users. CONCLUSIONS: Higher BP and HRV in dummy/pacifier users indicate increased sympathetic tone, which may serve as a protective mechanism against possible hypotension leading to SIDS; however, these effects were not apparent at 2-3 months, when the risk of SIDS is highest.",
author = "Stephanie Yiallourou and Hannah Poole and Pallavi Prathivadi and Alexsandria Odoi and Wong, {Flora Yuen-Wait} and Horne, {Rosemary Sylvia Claire}",
year = "2014",
doi = "10.1016/j.sleep.2014.07.011",
language = "English",
volume = "15",
pages = "1508 -- 1516",
journal = "Sleep Medicine",
issn = "1389-9457",
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number = "12",

}

The effects of dummy/pacifier use on infant blood pressure and autonomic activity during sleep. / Yiallourou, Stephanie; Poole, Hannah; Prathivadi, Pallavi; Odoi, Alexsandria; Wong, Flora Yuen-Wait; Horne, Rosemary Sylvia Claire.

In: Sleep Medicine, Vol. 15, No. 12, 2014, p. 1508 - 1516.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - The effects of dummy/pacifier use on infant blood pressure and autonomic activity during sleep

AU - Yiallourou, Stephanie

AU - Poole, Hannah

AU - Prathivadi, Pallavi

AU - Odoi, Alexsandria

AU - Wong, Flora Yuen-Wait

AU - Horne, Rosemary Sylvia Claire

PY - 2014

Y1 - 2014

N2 - Dummy/pacifier use is protective for sudden infant death syndrome (SIDS); however, the mechanism/s for this are unknown. As impaired cardiovascular control may be the underlying cause of SIDS, we assessed the effects of dummy/pacifier use on cardiovascular control during sleep within the first 6 months of life. METHODS: Term infants, divided into dummy/pacifier users and non-dummy/pacifier users, were studied at 2-4 weeks (n = 27), 2-3 months (n = 35) and 5-6 months (n = 31) using daytime polysomnography. Heart rate, blood pressure (BP), heart rate variability (HRV), blood pressure variability (BPV), and baroreflex sensitivity (BRS) were measured in triplicate 1-2-min epochs during quiet and active sleep in the supine and prone positions. RESULTS: Overall, during the non-sucking periods, in the prone position, the BP was higher (10-22 mmHg) in dummy/pacifier users compared to non-users at 2-4 weeks and 5-6 months (p <0.05 for both). HRV and BRS were higher in dummy/pacifier users compared to non-users at 2-4 weeks (p <0.05). Active sucking increased HRV and BPV, consistent with increased sympathetic activity in dummy/pacifier users. CONCLUSIONS: Higher BP and HRV in dummy/pacifier users indicate increased sympathetic tone, which may serve as a protective mechanism against possible hypotension leading to SIDS; however, these effects were not apparent at 2-3 months, when the risk of SIDS is highest.

AB - Dummy/pacifier use is protective for sudden infant death syndrome (SIDS); however, the mechanism/s for this are unknown. As impaired cardiovascular control may be the underlying cause of SIDS, we assessed the effects of dummy/pacifier use on cardiovascular control during sleep within the first 6 months of life. METHODS: Term infants, divided into dummy/pacifier users and non-dummy/pacifier users, were studied at 2-4 weeks (n = 27), 2-3 months (n = 35) and 5-6 months (n = 31) using daytime polysomnography. Heart rate, blood pressure (BP), heart rate variability (HRV), blood pressure variability (BPV), and baroreflex sensitivity (BRS) were measured in triplicate 1-2-min epochs during quiet and active sleep in the supine and prone positions. RESULTS: Overall, during the non-sucking periods, in the prone position, the BP was higher (10-22 mmHg) in dummy/pacifier users compared to non-users at 2-4 weeks and 5-6 months (p <0.05 for both). HRV and BRS were higher in dummy/pacifier users compared to non-users at 2-4 weeks (p <0.05). Active sucking increased HRV and BPV, consistent with increased sympathetic activity in dummy/pacifier users. CONCLUSIONS: Higher BP and HRV in dummy/pacifier users indicate increased sympathetic tone, which may serve as a protective mechanism against possible hypotension leading to SIDS; however, these effects were not apparent at 2-3 months, when the risk of SIDS is highest.

UR - http://www.sciencedirect.com/science/article/pii/S1389945714003542

U2 - 10.1016/j.sleep.2014.07.011

DO - 10.1016/j.sleep.2014.07.011

M3 - Article

VL - 15

SP - 1508

EP - 1516

JO - Sleep Medicine

JF - Sleep Medicine

SN - 1389-9457

IS - 12

ER -