TY - JOUR
T1 - The effects of dietary weight loss with or without exercise training on liver enzymes in obese metabolic syndrome subjects
AU - Straznicky, Nora
AU - Lambert, Elisabeth
AU - Grima, Mariee
AU - Eikelis, Nina
AU - Nestel, Paul
AU - Dawood, Tye
AU - Schlaich, Markus
AU - Masuo, Kazuko
AU - Chopra, Reena
AU - Sari, Carolina
AU - Dixon, John
AU - Tilbrook, Alan
AU - Lambert, Gavin
PY - 2012
Y1 - 2012
N2 - Aims: Insulin resistance and visceral adiposity are predisposing factors for fatty liver disease. The main objectives of this study were 1) to compare the effects of caloric restriction alone (CR) or together with moderate-intensity aerobic exercise training (CR+EX) on liver enzymes, a surrogate marker of liver injury, in obese metabolic syndrome (MetS) subjects and 2) to identify anthropometric, metabolic, cardiovascular and dietary predictors of changes in liver enzymes. Methods: Sedentary men and women (n=63), aged 55 + 6 (SD) years with body mass index 32.7 + 4.1 kg/m(2) and confirmed MetS, were randomized to 12-weeks CR, CR+EX or no treatment (Control). Results: Weight loss averaged 7.6 in the CR and 9.1 in the CR+EX group (time effect, P
AB - Aims: Insulin resistance and visceral adiposity are predisposing factors for fatty liver disease. The main objectives of this study were 1) to compare the effects of caloric restriction alone (CR) or together with moderate-intensity aerobic exercise training (CR+EX) on liver enzymes, a surrogate marker of liver injury, in obese metabolic syndrome (MetS) subjects and 2) to identify anthropometric, metabolic, cardiovascular and dietary predictors of changes in liver enzymes. Methods: Sedentary men and women (n=63), aged 55 + 6 (SD) years with body mass index 32.7 + 4.1 kg/m(2) and confirmed MetS, were randomized to 12-weeks CR, CR+EX or no treatment (Control). Results: Weight loss averaged 7.6 in the CR and 9.1 in the CR+EX group (time effect, P
UR - http://onlinelibrary.wiley.com/doi/10.1111/j.1463-1326.2011.01497.x/pdf
U2 - 10.1111/j.1463-1326.2011.01497.x
DO - 10.1111/j.1463-1326.2011.01497.x
M3 - Article
SN - 1462-8902
VL - 14
SP - 139
EP - 148
JO - Diabetes, Obesity and Metabolism
JF - Diabetes, Obesity and Metabolism
IS - 2
ER -