The effect of oxygen content during an initial sustained inflation on heart rate in asphyxiated near-term lambs

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Abstract

OBJECTIVE: At birth, an initial sustained inflation (SI) uniformly aerates the lungs, increases arterial oxygenation and rapidly improves circulatory recovery in asphyxiated newborns. We hypothesised that lung aeration, in the absence of an increase in arterial oxygenation, can increase heart rate (HR) in asphyxiated near-term lambs. INTERVENTIONS: Lambs were delivered and instrumented at 139+/-2 days of gestation. Asphyxia was induced by umbilical cord clamping and then delaying the onset of ventilation until mean carotid arterial pressures (CAPs) had decreased
Original languageEnglish
Pages (from-to)337 - 343
Number of pages7
JournalArchives of Disease in Childhood: Fetal and Neonatal Edition
Volume100
Issue number4
DOIs
Publication statusPublished - 2015

Cite this