TY - JOUR
T1 - The effect of lifestyle intervention on diabetes prevention by ethnicity
T2 - A systematic review of intervention characteristics using the tidier framework
AU - Chen, Mingling
AU - Ukke, Gebresilasea Gendisha
AU - Moran, Lisa J.
AU - Sood, Surbhi
AU - Bennett, Christie J.
AU - Khomami, Mahnaz Bahri
AU - Absetz, Pilvikki
AU - Teede, Helena
AU - Harrison, Cheryce L.
AU - Lim, Siew
N1 - Funding Information:
This research was funded by the National Health and Medical Research Council Centre for Research Excellence for Health in Preconception and Pregnancy (CRE-HiPP; APP1171142; C.L.H.); National Medical Health and Research Council Fellowship (S.L.); National Heart Foundation Future Leader Fellowship (L.J.M.); Australian Government Medical Research Future Fund Fellowship (H.T.); and Australian Government Research Training Program Scholarship (M.C.). The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/11
Y1 - 2021/11
N2 - Lifestyle intervention is effective in preventing type 2 diabetes mellitus (T2DM), but the efficacy of intervention components across different ethnic groups is less clear. This systematic review examined the effects of intervention characteristics of lifestyle interventions on diabetes incidence and weight loss by ethnicity using the Template for Intervention Description and Replication (TIDieR) framework. MEDLINE, EMBASE and other databases were searched for randomized and non-randomized controlled trials on lifestyle interventions (diet and/or physical activity) in adults at risk of T2DM. Ethnicity was categorized into European, South Asian, East and Southeast Asian, Middle Eastern, Latin American and African groups. Forty-five studies (18,789 participants) were included in the systematic review and 41 studies in meta-analysis. Meta-analysis showed a high number of intervention sessions was significantly associated with a greater reduction in diabetes incidence (P = 0.043) and weight (P = 0.015), while other intervention characteristics including intervention provider and delivery format did not alter the outcomes (all P > 0.05). Additionally, narrative synthesis showed long-term interventions (≥12 months) were associated with significant diabetes risk reduction for all ethnic groups, while short-term interventions (<12 months) were more effective in weight loss in most ethnic groups. There may be ethnic preferences for the optimal number of intervention sessions.
AB - Lifestyle intervention is effective in preventing type 2 diabetes mellitus (T2DM), but the efficacy of intervention components across different ethnic groups is less clear. This systematic review examined the effects of intervention characteristics of lifestyle interventions on diabetes incidence and weight loss by ethnicity using the Template for Intervention Description and Replication (TIDieR) framework. MEDLINE, EMBASE and other databases were searched for randomized and non-randomized controlled trials on lifestyle interventions (diet and/or physical activity) in adults at risk of T2DM. Ethnicity was categorized into European, South Asian, East and Southeast Asian, Middle Eastern, Latin American and African groups. Forty-five studies (18,789 participants) were included in the systematic review and 41 studies in meta-analysis. Meta-analysis showed a high number of intervention sessions was significantly associated with a greater reduction in diabetes incidence (P = 0.043) and weight (P = 0.015), while other intervention characteristics including intervention provider and delivery format did not alter the outcomes (all P > 0.05). Additionally, narrative synthesis showed long-term interventions (≥12 months) were associated with significant diabetes risk reduction for all ethnic groups, while short-term interventions (<12 months) were more effective in weight loss in most ethnic groups. There may be ethnic preferences for the optimal number of intervention sessions.
KW - Ethnicity
KW - Lifestyle intervention
KW - Systematic review
KW - Type 2 diabetes
UR - http://www.scopus.com/inward/record.url?scp=85119087327&partnerID=8YFLogxK
U2 - 10.3390/nu13114118
DO - 10.3390/nu13114118
M3 - Article
C2 - 34836372
AN - SCOPUS:85119087327
SN - 2072-6643
VL - 13
JO - Nutrients
JF - Nutrients
IS - 11
M1 - 4118
ER -
