The effect of intermittent antenatal iron supplementation on maternal and infant outcomes in rural Viet Nam: a cluster randomised trial

Sarah Hanieh; Tran Thu Ha; Julie A Simpson; Gerard J Casey; Nguyen Khuong; Dang D Thoang; Tran T Thuy; Sant-Rayn Pasricha; Thach Duc Tran; Tran Tuan; Terence D Dwyer; Jane Rosamond Woodward Fisher; Beverley-Ann Biggs

doi:10.1371/journal.pmed.1001470

The effect of intermittent antenatal iron supplementation on maternal and infant outcomes in rural Viet Nam: a cluster randomised trial

Sarah Hanieh, Tran Thu Ha, Julie A Simpson, Gerard J Casey, Nguyen Khuong, Dang D Thoang, Tran T Thuy, Sant-Rayn Pasricha, Thach Duc Tran, Tran Tuan, Terence D Dwyer, Jane Rosamond Woodward Fisher, Beverley-Ann Biggs

Health Systems Services & Policy

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45 Citations (Scopus)

Abstract

Anemia affects over 500 million women, and in pregnancy is associated with impaired maternal and infant outcomes. Intermittent antenatal iron supplementation is an attractive alternative to daily dosing; however, the impact of this strategy on infant outcomes remains unclear. We compared the effect of intermittent antenatal iron supplementation with daily iron supplementation on maternal and infant outcomes in rural Viet Nam. Methods and Findings This cluster randomised trial was conducted in Ha Nam province, Viet Nam. 1,258 pregnant women (

Original language	English
Pages (from-to)	1 - 15
Number of pages	15
Journal	PLoS Medicine
Volume	10
Issue number	6 (Art. No.: e1001470)
DOIs	https://doi.org/10.1371/journal.pmed.1001470
Publication status	Published - 2013

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10.1371/journal.pmed.1001470

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Hanieh, S., Ha, T. T., Simpson, J. A., Casey, G. J., Khuong, N., Thoang, D. D., Thuy, T. T., Pasricha, S.-R., Tran, T. D., Tuan, T., Dwyer, T. D., Fisher, J. R. W., & Biggs, B.-A. (2013). The effect of intermittent antenatal iron supplementation on maternal and infant outcomes in rural Viet Nam: a cluster randomised trial. PLoS Medicine, 10(6 (Art. No.: e1001470)), 1 - 15. https://doi.org/10.1371/journal.pmed.1001470

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abstract = "Anemia affects over 500 million women, and in pregnancy is associated with impaired maternal and infant outcomes. Intermittent antenatal iron supplementation is an attractive alternative to daily dosing; however, the impact of this strategy on infant outcomes remains unclear. We compared the effect of intermittent antenatal iron supplementation with daily iron supplementation on maternal and infant outcomes in rural Viet Nam. Methods and Findings This cluster randomised trial was conducted in Ha Nam province, Viet Nam. 1,258 pregnant women (",

author = "Sarah Hanieh and Ha, {Tran Thu} and Simpson, {Julie A} and Casey, {Gerard J} and Nguyen Khuong and Thoang, {Dang D} and Thuy, {Tran T} and Sant-Rayn Pasricha and Tran, {Thach Duc} and Tran Tuan and Dwyer, {Terence D} and Fisher, {Jane Rosamond Woodward} and Beverley-Ann Biggs",

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Hanieh, S, Ha, TT, Simpson, JA, Casey, GJ, Khuong, N, Thoang, DD, Thuy, TT, Pasricha, S-R, Tran, TD, Tuan, T, Dwyer, TD, Fisher, JRW & Biggs, B-A 2013, 'The effect of intermittent antenatal iron supplementation on maternal and infant outcomes in rural Viet Nam: a cluster randomised trial', PLoS Medicine, vol. 10, no. 6 (Art. No.: e1001470), pp. 1 - 15. https://doi.org/10.1371/journal.pmed.1001470

TY - JOUR

T1 - The effect of intermittent antenatal iron supplementation on maternal and infant outcomes in rural Viet Nam: a cluster randomised trial

AU - Hanieh, Sarah

AU - Ha, Tran Thu

AU - Simpson, Julie A

AU - Casey, Gerard J

AU - Khuong, Nguyen

AU - Thoang, Dang D

AU - Thuy, Tran T

AU - Pasricha, Sant-Rayn

AU - Tran, Thach Duc

AU - Tuan, Tran

AU - Dwyer, Terence D

AU - Fisher, Jane Rosamond Woodward

AU - Biggs, Beverley-Ann

PY - 2013

Y1 - 2013

N2 - Anemia affects over 500 million women, and in pregnancy is associated with impaired maternal and infant outcomes. Intermittent antenatal iron supplementation is an attractive alternative to daily dosing; however, the impact of this strategy on infant outcomes remains unclear. We compared the effect of intermittent antenatal iron supplementation with daily iron supplementation on maternal and infant outcomes in rural Viet Nam. Methods and Findings This cluster randomised trial was conducted in Ha Nam province, Viet Nam. 1,258 pregnant women (

AB - Anemia affects over 500 million women, and in pregnancy is associated with impaired maternal and infant outcomes. Intermittent antenatal iron supplementation is an attractive alternative to daily dosing; however, the impact of this strategy on infant outcomes remains unclear. We compared the effect of intermittent antenatal iron supplementation with daily iron supplementation on maternal and infant outcomes in rural Viet Nam. Methods and Findings This cluster randomised trial was conducted in Ha Nam province, Viet Nam. 1,258 pregnant women (

UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708703/pdf/pmed.1001470.pdf

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DO - 10.1371/journal.pmed.1001470

M3 - Article

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JO - PLoS Medicine

JF - PLoS Medicine

IS - 6 (Art. No.: e1001470)

ER -

The effect of intermittent antenatal iron supplementation on maternal and infant outcomes in rural Viet Nam: a cluster randomised trial

Abstract

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