The effect of gestational age at birth on post-term maturation of heart rate variability

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Abstract

Preterm birth delays maturation of autonomic cardiovascular control, reflected in reduced heart rate variability (HRV), in preterm compared to term infants at term-equivalent age. It has been suggested that immature cardiovascular control contributes to the increased risk for the Sudden Infant Death Syndrome (SIDS) in preterm infants. However, the effect of prone sleeping, the major SIDS risk factor, and of gestational age (GA) at birth on HRV have not been assessed in preterm infants beyond term-equivalent age. Subjects and Methods: Very preterm (n=21; mean GA 29.4?0.3wk), preterm (n=14; mean GA 33.5?0.3wk) and term (n=17; mean GA 40.1?0.3wk) infants were recruited and underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term corrected age (CA). Infants slept both supine and prone. HRV was assessed in the low frequency (LF) and high frequency (HF) ranges. Results: There was no effect of prone sleeping on HRV parameters in either preterm group. In term infants LF/HF was significantly elevated in the prone position in AS at 2-4 weeks (p
Original languageEnglish
Pages (from-to)1635 - 1644
Number of pages10
JournalSleep
Volume38
Issue number10
DOIs
Publication statusPublished - 2015

Cite this

@article{8400b275c3964782b8fd816c744e462f,
title = "The effect of gestational age at birth on post-term maturation of heart rate variability",
abstract = "Preterm birth delays maturation of autonomic cardiovascular control, reflected in reduced heart rate variability (HRV), in preterm compared to term infants at term-equivalent age. It has been suggested that immature cardiovascular control contributes to the increased risk for the Sudden Infant Death Syndrome (SIDS) in preterm infants. However, the effect of prone sleeping, the major SIDS risk factor, and of gestational age (GA) at birth on HRV have not been assessed in preterm infants beyond term-equivalent age. Subjects and Methods: Very preterm (n=21; mean GA 29.4?0.3wk), preterm (n=14; mean GA 33.5?0.3wk) and term (n=17; mean GA 40.1?0.3wk) infants were recruited and underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term corrected age (CA). Infants slept both supine and prone. HRV was assessed in the low frequency (LF) and high frequency (HF) ranges. Results: There was no effect of prone sleeping on HRV parameters in either preterm group. In term infants LF/HF was significantly elevated in the prone position in AS at 2-4 weeks (p",
author = "Karinna Fyfe and Stephanie Yiallourou and Wong, {Flora Yuen-Wait} and Alexsandria Odoi and Walker, {Adrian Mark} and Horne, {Rosemary Sylvia Claire}",
year = "2015",
doi = "10.5665/sleep.5064",
language = "English",
volume = "38",
pages = "1635 -- 1644",
journal = "Sleep",
issn = "0161-8105",
publisher = "Associated Professional Sleep Societies",
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The effect of gestational age at birth on post-term maturation of heart rate variability. / Fyfe, Karinna; Yiallourou, Stephanie; Wong, Flora Yuen-Wait; Odoi, Alexsandria; Walker, Adrian Mark; Horne, Rosemary Sylvia Claire.

In: Sleep, Vol. 38, No. 10, 2015, p. 1635 - 1644.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - The effect of gestational age at birth on post-term maturation of heart rate variability

AU - Fyfe, Karinna

AU - Yiallourou, Stephanie

AU - Wong, Flora Yuen-Wait

AU - Odoi, Alexsandria

AU - Walker, Adrian Mark

AU - Horne, Rosemary Sylvia Claire

PY - 2015

Y1 - 2015

N2 - Preterm birth delays maturation of autonomic cardiovascular control, reflected in reduced heart rate variability (HRV), in preterm compared to term infants at term-equivalent age. It has been suggested that immature cardiovascular control contributes to the increased risk for the Sudden Infant Death Syndrome (SIDS) in preterm infants. However, the effect of prone sleeping, the major SIDS risk factor, and of gestational age (GA) at birth on HRV have not been assessed in preterm infants beyond term-equivalent age. Subjects and Methods: Very preterm (n=21; mean GA 29.4?0.3wk), preterm (n=14; mean GA 33.5?0.3wk) and term (n=17; mean GA 40.1?0.3wk) infants were recruited and underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term corrected age (CA). Infants slept both supine and prone. HRV was assessed in the low frequency (LF) and high frequency (HF) ranges. Results: There was no effect of prone sleeping on HRV parameters in either preterm group. In term infants LF/HF was significantly elevated in the prone position in AS at 2-4 weeks (p

AB - Preterm birth delays maturation of autonomic cardiovascular control, reflected in reduced heart rate variability (HRV), in preterm compared to term infants at term-equivalent age. It has been suggested that immature cardiovascular control contributes to the increased risk for the Sudden Infant Death Syndrome (SIDS) in preterm infants. However, the effect of prone sleeping, the major SIDS risk factor, and of gestational age (GA) at birth on HRV have not been assessed in preterm infants beyond term-equivalent age. Subjects and Methods: Very preterm (n=21; mean GA 29.4?0.3wk), preterm (n=14; mean GA 33.5?0.3wk) and term (n=17; mean GA 40.1?0.3wk) infants were recruited and underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term corrected age (CA). Infants slept both supine and prone. HRV was assessed in the low frequency (LF) and high frequency (HF) ranges. Results: There was no effect of prone sleeping on HRV parameters in either preterm group. In term infants LF/HF was significantly elevated in the prone position in AS at 2-4 weeks (p

UR - http://www.ncbi.nlm.nih.gov/pubmed/25902805

U2 - 10.5665/sleep.5064

DO - 10.5665/sleep.5064

M3 - Article

VL - 38

SP - 1635

EP - 1644

JO - Sleep

JF - Sleep

SN - 0161-8105

IS - 10

ER -