TY - JOUR
T1 - The effect of gestational age at birth on post-term maturation of heart rate variability
AU - Fyfe, Karinna
AU - Yiallourou, Stephanie
AU - Wong, Flora Yuen-Wait
AU - Odoi, Alexsandria
AU - Walker, Adrian Mark
AU - Horne, Rosemary Sylvia Claire
PY - 2015
Y1 - 2015
N2 - Preterm birth delays maturation of autonomic cardiovascular control, reflected in reduced heart rate variability (HRV), in preterm compared to term infants at term-equivalent age. It has been suggested that immature cardiovascular control contributes to the increased risk for the Sudden Infant Death Syndrome (SIDS) in preterm infants. However, the effect of prone sleeping, the major SIDS risk factor, and of gestational age (GA)
at birth on HRV have not been assessed in preterm infants beyond term-equivalent age.
Subjects and Methods: Very preterm (n=21; mean GA 29.4?0.3wk), preterm (n=14; mean GA 33.5?0.3wk) and term (n=17; mean GA 40.1?0.3wk) infants were recruited and underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term corrected age (CA). Infants slept both supine and prone. HRV was assessed in the low frequency (LF) and high frequency (HF) ranges.
Results: There was no effect of prone sleeping on HRV parameters in either preterm group. In term infants LF/HF was significantly elevated in the prone position in AS at 2-4 weeks (p
AB - Preterm birth delays maturation of autonomic cardiovascular control, reflected in reduced heart rate variability (HRV), in preterm compared to term infants at term-equivalent age. It has been suggested that immature cardiovascular control contributes to the increased risk for the Sudden Infant Death Syndrome (SIDS) in preterm infants. However, the effect of prone sleeping, the major SIDS risk factor, and of gestational age (GA)
at birth on HRV have not been assessed in preterm infants beyond term-equivalent age.
Subjects and Methods: Very preterm (n=21; mean GA 29.4?0.3wk), preterm (n=14; mean GA 33.5?0.3wk) and term (n=17; mean GA 40.1?0.3wk) infants were recruited and underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term corrected age (CA). Infants slept both supine and prone. HRV was assessed in the low frequency (LF) and high frequency (HF) ranges.
Results: There was no effect of prone sleeping on HRV parameters in either preterm group. In term infants LF/HF was significantly elevated in the prone position in AS at 2-4 weeks (p
UR - http://www.ncbi.nlm.nih.gov/pubmed/25902805
U2 - 10.5665/sleep.5064
DO - 10.5665/sleep.5064
M3 - Article
SN - 0161-8105
VL - 38
SP - 1635
EP - 1644
JO - Sleep
JF - Sleep
IS - 10
ER -