The Economics of Malaria Vaccine Development

Magdalena Plebanski, Katie L. Flanagan

Research output: Contribution to journal › Comment / Debate › Other › peer-review

2 Citations (Scopus)

Abstract

Vaccines that do not take a comprehensive endpoint view of the pathogen population they want to tackle early in their developmental process, may find it financially prohibitive to redesign them once they have progressed down a costly regulatory and human trial pathway. Specifically, the lead malaria vaccine candidate RTS,S has limited ability to tackle parasite polymorphism and may induce sex-specific nonspecific effects (NSEs).

Original languageEnglish
Pages (from-to)154-156
Number of pages3
JournalTrends in Parasitology
Volume33
Issue number3
DOIs
Publication statusPublished - 1 Mar 2017

Cite this

Plebanski, Magdalena ; Flanagan, Katie L. / The Economics of Malaria Vaccine Development. In: Trends in Parasitology. 2017 ; Vol. 33, No. 3. pp. 154-156.
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Plebanski, M & Flanagan, KL 2017, 'The Economics of Malaria Vaccine Development', Trends in Parasitology, vol. 33, no. 3, pp. 154-156. https://doi.org/10.1016/j.pt.2017.01.006

The Economics of Malaria Vaccine Development. / Plebanski, Magdalena; Flanagan, Katie L.

In: Trends in Parasitology, Vol. 33, No. 3, 01.03.2017, p. 154-156.

Research output: Contribution to journal › Comment / Debate › Other › peer-review

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AB - Vaccines that do not take a comprehensive endpoint view of the pathogen population they want to tackle early in their developmental process, may find it financially prohibitive to redesign them once they have progressed down a costly regulatory and human trial pathway. Specifically, the lead malaria vaccine candidate RTS,S has limited ability to tackle parasite polymorphism and may induce sex-specific nonspecific effects (NSEs).

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Plebanski M, Flanagan KL. The Economics of Malaria Vaccine Development. Trends in Parasitology. 2017 Mar 1;33(3):154-156. https://doi.org/10.1016/j.pt.2017.01.006

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