THE DEVELOPMENT OF CUSHING'S SYNDROME FROM A PREVIOUSLY SILENT PITUITARY TUMOUR

M. E. COOPER, R. M.L. MURRAY, R. KALNINS, J. WOODWARD, G. JERUMS

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Abstract

Abstract A 60 year old woman originally presented with headache. Investigations revealed a pituitary tumour and endocrine investigations at that time showed normal plasma Cortisol levels. Seven years after removal of this tumour, the patient developed the clinical and biochemical features of Cushing's disease. Immunoperoxidase staining of the original tumour was positive for adrenocor‐ticotrophic hormone. This report suggests that immunocytochemistry may have an important role in the routine evaluation of pituitary tumours.

Original languageEnglish
Pages (from-to)249-251
Number of pages3
JournalAustralian and New Zealand Journal of Medicine
Volume17
Issue number2
DOIs
Publication statusPublished - Apr 1987
Externally publishedYes

Keywords

  • Adrenocorticotrophic hormone
  • corticotroph adenoma.
  • Cushing's syndrome
  • immunoperoxidase
  • pituitary

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