Abstract
Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related targets and pathways is the ultimate treatment goal for DM. Nanotechnology has offered some exciting possibilities in biomedical and drug delivery applications. Zinc oxide nanoparticles (ZnO-NPs), a novel agent to deliver zinc, have great implications in many disease therapies including DM. This review summarizes the pharmacological mechanisms by which ZnO-NPs alleviate DM and diabetic complications. Research implications and future perspectives were also discussed.
Original language | English |
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Article number | 117011 |
Number of pages | 7 |
Journal | Life Sciences |
Volume | 239 |
DOIs | |
Publication status | Published - 15 Dec 2019 |
Keywords
- Diabetes mellitus
- Hyperglycemia
- Hypoglycemic agents
- Insulin
- Nanoparticles
- Zinc oxide