The current and future perspectives of zinc oxide nanoparticles in the treatment of diabetes mellitus

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Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related targets and pathways is the ultimate treatment goal for DM. Nanotechnology has offered some exciting possibilities in biomedical and drug delivery applications. Zinc oxide nanoparticles (ZnO-NPs), a novel agent to deliver zinc, have great implications in many disease therapies including DM. This review summarizes the pharmacological mechanisms by which ZnO-NPs alleviate DM and diabetic complications. Research implications and future perspectives were also discussed.

Original languageEnglish
Article number117011
Number of pages7
JournalLife Sciences
Publication statusPublished - 15 Dec 2019


  • Diabetes mellitus
  • Hyperglycemia
  • Hypoglycemic agents
  • Insulin
  • Nanoparticles
  • Zinc oxide

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