Abstract
Ioannidis and colleagues show that the gene DMRT1 is the master regulator of testis development in the chicken. Yet, remarkably, when this gene is deleted in genetic males and gonads form ovaries, the body remains male. This debunks the notion that somatic sex is driven primarily by hormones in birds.
Original language | English |
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Pages (from-to) | 496-497 |
Number of pages | 2 |
Journal | Trends in Genetics |
Volume | 37 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2021 |
Keywords
- avian sex
- chicken embryo
- DMRT1
- gonad
- gonadal sex differentiation
- sex determination