The copper-catalyzed oxidative N-acylation of sulfoximines

Long Wang, Daniel Priebbenow, LiangHua Zou, Carsten Bolm

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45 Citations (Scopus)

Abstract

An oxidative cross-coupling reaction between aldehydes and sulfoximines involving dual C-H/N-H functionalization has been developed. This reaction process is facilitated by a simple copper catalyst (1 mol loading) and tert-butyl hydroperoxide (TBHP) as the oxidant and proceeds under mild reaction conditions to afford a series of valuable N-acylated sulfoximine derivatives in excellent yields.
Original languageEnglish
Pages (from-to)1490 - 1494
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume355
Issue number8
DOIs
Publication statusPublished - 2013
Externally publishedYes

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