The Concise Guide to PHARMACOLOGY 2015/16

Overview

CGTP Collaborators

Research output: Contribution to journalReview ArticleOtherpeer-review

147 Citations (Scopus)

Abstract

The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.Wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.

Original languageEnglish
Pages (from-to)5729-5743
Number of pages15
JournalBritish Journal of Pharmacology
Volume172
Issue number24
DOIs
Publication statusPublished - 1 Dec 2015

Cite this

CGTP Collaborators. / The Concise Guide to PHARMACOLOGY 2015/16 : Overview. In: British Journal of Pharmacology. 2015 ; Vol. 172, No. 24. pp. 5729-5743.
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abstract = "The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.Wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.",
author = "Alexander, {Stephen P.H.} and Eamonn Kelly and Neil Marrion and Peters, {John A.} and Benson, {Helen E.} and Elena Faccenda and Pawson, {Adam J.} and Sharman, {Joanna L.} and Christopher Southan and {Peter Buneman}, O. and Catterall, {William A.} and Cidlowski, {John A.} and Davenport, {Anthony P.} and Doriano Fabbro and Grace Fan and McGrath, {John C.} and Michael Spedding and Davies, {Jamie A.} and R. Aldrich and B. Attali and B{\"a}ck, {M. L.} and Barnes, {N. M.} and R. Bathgate and Beart, {P. M.} and E. Becirovic and M. Biel and Birdsall, {N. J.} and D. Boison and H. Br{\"a}uner-Osborne and S. Br{\"o}er and C. Bryant and G. Burnstock and T. Burris and D. Cain and G. Calo and Chan, {S. L.} and Chandy, {K. G.} and N. Chiang and S. Christakos and A. Christopoulos and Chun, {J. J.} and Chung, {J. J.} and Clapham, {D. E.} and Connor, {M. A.} and L. Coons and Cox, {H. M.} and Dautzenberg, {F. M.} and G. Dent and Douglas, {S. D.} and Dubocovich, {M. L.} and Edwards, {D. P.} and R. Farndale and Fong, {T. M.} and D. Forrest and Fowler, {C. J.} and P. Fuller and Gainetdinov, {R. R.} and Gershengorn, {M. A.} and A. Goldin and Goldstein, {S. A.} and Grimm, {S. L.} and S. Grissmer and Gundlach, {A. L.} and B. Hagenbuch and Hammond, {J. R.} and Hancox, {J. C.} and S. Hartig and Hauger, {R. L.} and Hay, {D. L.} and T. H{\'e}bert and Hollenberg, {A. N.} and Holliday, {N. D.} and D. Hoyer and Ijzerman, {A. P.} and Inui, {K. I.} and S. Ishii and Jacobson, {K. A.} and Jan, {L. Y.} and Jarvis, {G. E.} and R. Jensen and A. Jetten and R. Jockers and Kaczmarek, {L. K.} and Y. Kanai and Kang, {H. S.} and S. Karnik and Kerr, {I. D.} and Korach, {K. S.} and Lange, {C. A.} and D. Larhammar and F. Leeb-Lundberg and R. Leurs and Lolait, {S. J.} and D. Macewan and Maguire, {J. J.} and May, {J. M.} and J. Mazella and McArdle, {C. A.} and McDonnell, {D. P.} and Michel, {M. C.} and Miller, {L. J.} and V. Mitolo and T. Monie and Monk, {P. N.} and B. Mouillac and Murphy, {P. M.} and Nahon, {J. L.} and J. Nerbonne and Nichols, {C. G.} and X. Norel and R. Oakley and S. Offermanns and Palmer, {L. G.} and Panaro, {M. A.} and E. Perez-Reyes and Pertwee, {R. G.} and Pike, {J. W.} and Pin, {J. P.} and S. Pintor and Plant, {L. D.} and Poyner, {D. R.} and Prossnitz, {E. R.} and S. Pyne and D. Ren and Richer, {J. K.} and P. Rondard and Ross, {R. A.} and H. Sackin and R. Safi and Sanguinetti, {M. C.} and Sartorius, {C. A.} and Segaloff, {D. L.} and Sladek, {F. M.} and G. Stewart and Stoddart, {L. A.} and J. Striessnig and Summers, {R. J.} and Y. Takeda and M. Tetel and L. Toll and Trimmer, {J. S.} and Tsai, {M. J.} and Tsai, {S. Y.} and S. Tucker and Usdin, {T. B.} and Vilargada, {J. P.} and M. Vore and Ward, {D. T.} and Waxman, {S. G.} and P. Webb and Wei, {A. D.} and N. Weigel and Willars, {G. B.} and C. Winrow and Wong, {S. S.} and H. Wulff and Ye, {R. D.} and M. Young and Zajac, {J. M.} and {CGTP Collaborators}",
year = "2015",
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language = "English",
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}

The Concise Guide to PHARMACOLOGY 2015/16 : Overview. / CGTP Collaborators.

In: British Journal of Pharmacology, Vol. 172, No. 24, 01.12.2015, p. 5729-5743.

Research output: Contribution to journalReview ArticleOtherpeer-review

TY - JOUR

T1 - The Concise Guide to PHARMACOLOGY 2015/16

T2 - Overview

AU - Alexander, Stephen P.H.

AU - Kelly, Eamonn

AU - Marrion, Neil

AU - Peters, John A.

AU - Benson, Helen E.

AU - Faccenda, Elena

AU - Pawson, Adam J.

AU - Sharman, Joanna L.

AU - Southan, Christopher

AU - Peter Buneman, O.

AU - Catterall, William A.

AU - Cidlowski, John A.

AU - Davenport, Anthony P.

AU - Fabbro, Doriano

AU - Fan, Grace

AU - McGrath, John C.

AU - Spedding, Michael

AU - Davies, Jamie A.

AU - Aldrich, R.

AU - Attali, B.

AU - Bäck, M. L.

AU - Barnes, N. M.

AU - Bathgate, R.

AU - Beart, P. M.

AU - Becirovic, E.

AU - Biel, M.

AU - Birdsall, N. J.

AU - Boison, D.

AU - Bräuner-Osborne, H.

AU - Bröer, S.

AU - Bryant, C.

AU - Burnstock, G.

AU - Burris, T.

AU - Cain, D.

AU - Calo, G.

AU - Chan, S. L.

AU - Chandy, K. G.

AU - Chiang, N.

AU - Christakos, S.

AU - Christopoulos, A.

AU - Chun, J. J.

AU - Chung, J. J.

AU - Clapham, D. E.

AU - Connor, M. A.

AU - Coons, L.

AU - Cox, H. M.

AU - Dautzenberg, F. M.

AU - Dent, G.

AU - Douglas, S. D.

AU - Dubocovich, M. L.

AU - Edwards, D. P.

AU - Farndale, R.

AU - Fong, T. M.

AU - Forrest, D.

AU - Fowler, C. J.

AU - Fuller, P.

AU - Gainetdinov, R. R.

AU - Gershengorn, M. A.

AU - Goldin, A.

AU - Goldstein, S. A.

AU - Grimm, S. L.

AU - Grissmer, S.

AU - Gundlach, A. L.

AU - Hagenbuch, B.

AU - Hammond, J. R.

AU - Hancox, J. C.

AU - Hartig, S.

AU - Hauger, R. L.

AU - Hay, D. L.

AU - Hébert, T.

AU - Hollenberg, A. N.

AU - Holliday, N. D.

AU - Hoyer, D.

AU - Ijzerman, A. P.

AU - Inui, K. I.

AU - Ishii, S.

AU - Jacobson, K. A.

AU - Jan, L. Y.

AU - Jarvis, G. E.

AU - Jensen, R.

AU - Jetten, A.

AU - Jockers, R.

AU - Kaczmarek, L. K.

AU - Kanai, Y.

AU - Kang, H. S.

AU - Karnik, S.

AU - Kerr, I. D.

AU - Korach, K. S.

AU - Lange, C. A.

AU - Larhammar, D.

AU - Leeb-Lundberg, F.

AU - Leurs, R.

AU - Lolait, S. J.

AU - Macewan, D.

AU - Maguire, J. J.

AU - May, J. M.

AU - Mazella, J.

AU - McArdle, C. A.

AU - McDonnell, D. P.

AU - Michel, M. C.

AU - Miller, L. J.

AU - Mitolo, V.

AU - Monie, T.

AU - Monk, P. N.

AU - Mouillac, B.

AU - Murphy, P. M.

AU - Nahon, J. L.

AU - Nerbonne, J.

AU - Nichols, C. G.

AU - Norel, X.

AU - Oakley, R.

AU - Offermanns, S.

AU - Palmer, L. G.

AU - Panaro, M. A.

AU - Perez-Reyes, E.

AU - Pertwee, R. G.

AU - Pike, J. W.

AU - Pin, J. P.

AU - Pintor, S.

AU - Plant, L. D.

AU - Poyner, D. R.

AU - Prossnitz, E. R.

AU - Pyne, S.

AU - Ren, D.

AU - Richer, J. K.

AU - Rondard, P.

AU - Ross, R. A.

AU - Sackin, H.

AU - Safi, R.

AU - Sanguinetti, M. C.

AU - Sartorius, C. A.

AU - Segaloff, D. L.

AU - Sladek, F. M.

AU - Stewart, G.

AU - Stoddart, L. A.

AU - Striessnig, J.

AU - Summers, R. J.

AU - Takeda, Y.

AU - Tetel, M.

AU - Toll, L.

AU - Trimmer, J. S.

AU - Tsai, M. J.

AU - Tsai, S. Y.

AU - Tucker, S.

AU - Usdin, T. B.

AU - Vilargada, J. P.

AU - Vore, M.

AU - Ward, D. T.

AU - Waxman, S. G.

AU - Webb, P.

AU - Wei, A. D.

AU - Weigel, N.

AU - Willars, G. B.

AU - Winrow, C.

AU - Wong, S. S.

AU - Wulff, H.

AU - Ye, R. D.

AU - Young, M.

AU - Zajac, J. M.

AU - CGTP Collaborators

PY - 2015/12/1

Y1 - 2015/12/1

N2 - The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.Wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.

AB - The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.Wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.

UR - http://www.scopus.com/inward/record.url?scp=84949818216&partnerID=8YFLogxK

U2 - 10.1111/bph.13347

DO - 10.1111/bph.13347

M3 - Review Article

VL - 172

SP - 5729

EP - 5743

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 1476-5381

IS - 24

ER -