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The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy

  • Julie Cao
  • , Elizabeth Siew-Sun Ng
  • , Donald McNaughton
  • , Edouard Stanley
  • , Andrew George Elefanty
  • , Mark J Tobin
  • , Philip Robert Heraud

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.
Original languageEnglish
Pages (from-to)17453 - 17476
Number of pages24
JournalInternational Journal of Molecular Sciences
Volume14
Issue number9
DOIs
Publication statusPublished - 2013

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