The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy

Julie Cao, Elizabeth Siew-Sun Ng, Donald McNaughton, Edouard Stanley, Andrew George Elefanty, Mark J Tobin, Philip Robert Heraud

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.
Original languageEnglish
Pages (from-to)17453 - 17476
Number of pages24
JournalInternational Journal of Molecular Sciences
Volume14
Issue number9
DOIs
Publication statusPublished - 2013

Cite this

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title = "The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy",
abstract = "Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.",
author = "Julie Cao and Ng, {Elizabeth Siew-Sun} and Donald McNaughton and Edouard Stanley and Elefanty, {Andrew George} and Tobin, {Mark J} and Heraud, {Philip Robert}",
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The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy. / Cao, Julie; Ng, Elizabeth Siew-Sun; McNaughton, Donald; Stanley, Edouard; Elefanty, Andrew George; Tobin, Mark J; Heraud, Philip Robert.

In: International Journal of Molecular Sciences, Vol. 14, No. 9, 2013, p. 17453 - 17476.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Cao, Julie

AU - Ng, Elizabeth Siew-Sun

AU - McNaughton, Donald

AU - Stanley, Edouard

AU - Elefanty, Andrew George

AU - Tobin, Mark J

AU - Heraud, Philip Robert

PY - 2013

Y1 - 2013

N2 - Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.

AB - Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.

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DO - 10.3390/ijms140917453

M3 - Article

VL - 14

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EP - 17476

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1422-0067

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