The catalysis of nitrosation by thiocyanate from saliva

E. Boyland; E. Nice; K. Williams

doi:10.1016/0015-6264(71)90151-9

The catalysis of nitrosation by thiocyanate from saliva

E. Boyland, E. Nice, K. Williams

Research output: Contribution to journal › Article › Research › peer-review

76 Citations (Scopus)

Abstract

Experiments with N-methylaniline and morpholine have shown that thiocyanate, a normal constituent of human saliva, has a pronounced catalytic effect on the reaction between nitrite and secondary amines to form nitrosamines. After the ingestion of food containing nitrite, therefore, the presence of saliva may cause the formation of nitrosamines in the stomach to be greater than has previously been suspected.

Original language	English
Pages (from-to)	639-643
Number of pages	5
Journal	Food and Cosmetics Toxicology
Volume	9
Issue number	5
DOIs	https://doi.org/10.1016/0015-6264(71)90151-9
Publication status	Published - 1 Jan 1971
Externally published	Yes

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10.1016/0015-6264(71)90151-9

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Cite this

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title = "The catalysis of nitrosation by thiocyanate from saliva",

abstract = "Experiments with N-methylaniline and morpholine have shown that thiocyanate, a normal constituent of human saliva, has a pronounced catalytic effect on the reaction between nitrite and secondary amines to form nitrosamines. After the ingestion of food containing nitrite, therefore, the presence of saliva may cause the formation of nitrosamines in the stomach to be greater than has previously been suspected.",

author = "E. Boyland and E. Nice and K. Williams",

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AU - Williams, K.

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N2 - Experiments with N-methylaniline and morpholine have shown that thiocyanate, a normal constituent of human saliva, has a pronounced catalytic effect on the reaction between nitrite and secondary amines to form nitrosamines. After the ingestion of food containing nitrite, therefore, the presence of saliva may cause the formation of nitrosamines in the stomach to be greater than has previously been suspected.

AB - Experiments with N-methylaniline and morpholine have shown that thiocyanate, a normal constituent of human saliva, has a pronounced catalytic effect on the reaction between nitrite and secondary amines to form nitrosamines. After the ingestion of food containing nitrite, therefore, the presence of saliva may cause the formation of nitrosamines in the stomach to be greater than has previously been suspected.

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