TY - JOUR
T1 - The Burns Evaluation and Mortality Study (BEAMS): predicting deaths in Australian and New Zealand burn patients admitted to intensive care with burns
AU - Moore, Edwina Caroline
AU - Pilcher, David V
AU - Bailey, Michael John
AU - Stephens, Hugh
AU - Cleland, Heather
PY - 2013
Y1 - 2013
N2 - An understanding of prognosis following burns is important. It alleviates patient and familial stress, provides a framework
for better resource use, and facilitates benchmarking of performance between specialist centers.
METHODS: Data were collected from eight tertiary referral burns centers in Australia and New Zealand. Our aim was to identify factors
independently associated with mortality to develop a mortality prediction model, which accurately quantifies the risk of death
among adults with burns who require intensive care.
RESULTS: Between January 2005 and December 2011, 1,715 patients were admitted to intensive care unit with acute thermal burns. The
mean (SD) age was 41.1 (18.0) years, and 20.3 (n = 348) were female. Median percentage of total body surface area was
17 (6Y35 ) and percent full-thickness surface area was 4 (0Y20 ). Inhalational injury was documented as present in
36.2 . Accidental injury was the most common etiology of burn (70.4 ) and most frequently via a flame (68.3 ). Overall
hospital mortality was 10.9 (n = 187). Independent risk factors for death were age (odds ratio [OR], 1.08; 95 confidence
interval [CI], 1.06Y1.10; p G 0.001), percentage of full-thickness surface area (OR, 1.07; 95 CI 1.06Y1.08; p G 0.001), and
Acute Physiology and Chronic Health Evaluation II score excluding age (OR, 1.11; 95 CI, 1.07Y1.15; p G 0.001) and female
sex (OR, 3.35; 95 CI, 1.84Y6.11; p = 0.001). There was no association between inhalational injury or deliberate self-harm
and death, as well as etiology or type of burn.
CONCLUSION: A highly discriminatory mortality prediction model was developed using logistic regression. Risk of death following major
burns can be predicted from a combination of physiologic and burns specific parameters. Female sex is a highly significant risk
factor. (J Trauma Acute Care Surg. 2013;75: 298Y303. Copyright * 2013 by Lippincott Williams Wilkins)
LEVEL OF EVIDENCE: Prognostic study, level I
AB - An understanding of prognosis following burns is important. It alleviates patient and familial stress, provides a framework
for better resource use, and facilitates benchmarking of performance between specialist centers.
METHODS: Data were collected from eight tertiary referral burns centers in Australia and New Zealand. Our aim was to identify factors
independently associated with mortality to develop a mortality prediction model, which accurately quantifies the risk of death
among adults with burns who require intensive care.
RESULTS: Between January 2005 and December 2011, 1,715 patients were admitted to intensive care unit with acute thermal burns. The
mean (SD) age was 41.1 (18.0) years, and 20.3 (n = 348) were female. Median percentage of total body surface area was
17 (6Y35 ) and percent full-thickness surface area was 4 (0Y20 ). Inhalational injury was documented as present in
36.2 . Accidental injury was the most common etiology of burn (70.4 ) and most frequently via a flame (68.3 ). Overall
hospital mortality was 10.9 (n = 187). Independent risk factors for death were age (odds ratio [OR], 1.08; 95 confidence
interval [CI], 1.06Y1.10; p G 0.001), percentage of full-thickness surface area (OR, 1.07; 95 CI 1.06Y1.08; p G 0.001), and
Acute Physiology and Chronic Health Evaluation II score excluding age (OR, 1.11; 95 CI, 1.07Y1.15; p G 0.001) and female
sex (OR, 3.35; 95 CI, 1.84Y6.11; p = 0.001). There was no association between inhalational injury or deliberate self-harm
and death, as well as etiology or type of burn.
CONCLUSION: A highly discriminatory mortality prediction model was developed using logistic regression. Risk of death following major
burns can be predicted from a combination of physiologic and burns specific parameters. Female sex is a highly significant risk
factor. (J Trauma Acute Care Surg. 2013;75: 298Y303. Copyright * 2013 by Lippincott Williams Wilkins)
LEVEL OF EVIDENCE: Prognostic study, level I
UR - http://www.ncbi.nlm.nih.gov/pubmed/23887563
U2 - 10.1097/TA.0b013e318295409d
DO - 10.1097/TA.0b013e318295409d
M3 - Article
SN - 2163-0755
VL - 75
SP - 298
EP - 303
JO - The Journal of Trauma and Acute Care Surgery
JF - The Journal of Trauma and Acute Care Surgery
IS - 2
ER -