Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 509 - 515 |
| Number of pages | 7 |
| Journal | Resuscitation |
| Volume | 85 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2014 |
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The association between systolic blood pressure on arrival at hospital and outcome in adults surviving from out-of-hospital cardiac arrests of presumed cardiac aetiology. / Bray, Janet Elizabeth; Bernard, Stephen Anthony; Cantwell, Kate; Stephenson, Michael William; Smith, Karen Louise.
In: Resuscitation, Vol. 85, No. 4, 2014, p. 509 - 515.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - The association between systolic blood pressure on arrival at hospital and outcome in adults surviving from out-of-hospital cardiac arrests of presumed cardiac aetiology
AU - Bray, Janet Elizabeth
AU - Bernard, Stephen Anthony
AU - Cantwell, Kate
AU - Stephenson, Michael William
AU - Smith, Karen Louise
PY - 2014
Y1 - 2014
N2 - Background: The optimal blood pressure target following successful resuscitation from out-of-hospital cardiac arrest (OHCA) is uncertain. This study aimed to explore the association between level of systolic blood pressure (SBP) on arrival at hospital and survival to hospital discharge. Methods: We analysed eligible OHCAs occurring between January 2003 and December 2011 from the Victorian Ambulance Cardiac Arrest Register (VACAR). Inclusion criteria were: adults (=18 years), presumed cardiac aetiology, not paramedic witnessed, and ROSC at hospital arrival. Multivariate logistic regression models were performed by initial rhythm (shockable/non-shockable) to examine the relationship between SBP at hospital arrival in 10 mmHg increments and survival to hospital discharge. Models were adjusted for known predictors of survival, including duration of arrest. Results: Of 3620 eligible cases, 14 were hypotensive (SBP <90 mmHg) on hospital arrival (10 shockable and 19 non-shockable). For patients in shockable rhythms, discharge survival was maximal at 120-129 mmHg (54 ), and in the adjusted model (=120 mmHg as reference) SBP decrements below 90 mmHg were associated with lower survival: 80-89 mmHg AOR = 0.49 (95 CI: 0.24-0.95);
AB - Background: The optimal blood pressure target following successful resuscitation from out-of-hospital cardiac arrest (OHCA) is uncertain. This study aimed to explore the association between level of systolic blood pressure (SBP) on arrival at hospital and survival to hospital discharge. Methods: We analysed eligible OHCAs occurring between January 2003 and December 2011 from the Victorian Ambulance Cardiac Arrest Register (VACAR). Inclusion criteria were: adults (=18 years), presumed cardiac aetiology, not paramedic witnessed, and ROSC at hospital arrival. Multivariate logistic regression models were performed by initial rhythm (shockable/non-shockable) to examine the relationship between SBP at hospital arrival in 10 mmHg increments and survival to hospital discharge. Models were adjusted for known predictors of survival, including duration of arrest. Results: Of 3620 eligible cases, 14 were hypotensive (SBP <90 mmHg) on hospital arrival (10 shockable and 19 non-shockable). For patients in shockable rhythms, discharge survival was maximal at 120-129 mmHg (54 ), and in the adjusted model (=120 mmHg as reference) SBP decrements below 90 mmHg were associated with lower survival: 80-89 mmHg AOR = 0.49 (95 CI: 0.24-0.95);
UR - http://www.sciencedirect.com/science/article/pii/S0300957213008976
U2 - 10.1016/j.resuscitation.2013.12.005
DO - 10.1016/j.resuscitation.2013.12.005
M3 - Article
VL - 85
SP - 509
EP - 515
JO - Resuscitation
JF - Resuscitation
SN - 0300-9572
IS - 4
ER -