There is great concern about how landscape change will affect the persistence of native biota, and the services they provide to human wellbeing. Of fundamental concern is the effect on population processes — birth and death rates, migration and genetic exchange. Molecular ecology and landscape genetics make contributions to the analysis and monitoring of landscape change that are otherwise inaccessible. They can yield powerful and unambiguous information about where individuals and species move, with whom they reproduce, and what landscape features and arrangements impact their movement. These data can feed into modelling of population persistence. It is a common misconception that genetic signatures of landscape change take many generations to be detectable. Recent methods detect changes in population processes over very short timeframes, such as years to decades. It is surprising to many non-geneticists that these methods are: (a) available now and wholeheartedly applied by management agencies elsewhere in the world, and (b) highly costeffective. We summarise the application of selectively neutral genetic markers in landscape management.