The apoptosis pathway and the genetic predisposition to Achilles Tendinopathy

Erica-Mari Nell; Lize van der Merwe; Jillianne Leigh Cook; Christopher J Handley; Malcolm Collins; Alison V September

doi:10.1002/jor.22144

The apoptosis pathway and the genetic predisposition to Achilles Tendinopathy

Erica-Mari Nell, Lize van der Merwe, Jillianne Leigh Cook, Christopher J Handley, Malcolm Collins, Alison V September

Physiotherapy

Research output: Contribution to journal › Article › Research › peer-review

59 Citations (Scopus)

Abstract

Achilles tendinopathy (AT) is a degenerative condition for which several risk factors have been implicated including components of the inflammatory pathway. The aim was to assess functional variants within genes encoding components of the apoptosis signaling cascade and the effectiveness of a polygenic apoptosis profile to capture tendinopathy (TEN) risk

Original language	English
Pages (from-to)	1719 - 1724
Number of pages	6
Journal	Journal of Orthopaedic Research
Volume	30
Issue number	11
DOIs	https://doi.org/10.1002/jor.22144
Publication status	Published - 2012

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10.1002/jor.22144

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title = "The apoptosis pathway and the genetic predisposition to Achilles Tendinopathy",

abstract = "Achilles tendinopathy (AT) is a degenerative condition for which several risk factors have been implicated including components of the inflammatory pathway. The aim was to assess functional variants within genes encoding components of the apoptosis signaling cascade and the effectiveness of a polygenic apoptosis profile to capture tendinopathy (TEN) risk",

author = "Erica-Mari Nell and {van der Merwe}, Lize and Cook, {Jillianne Leigh} and Handley, {Christopher J} and Malcolm Collins and September, {Alison V}",

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AU - Nell, Erica-Mari

AU - van der Merwe, Lize

AU - Cook, Jillianne Leigh

AU - Handley, Christopher J

AU - Collins, Malcolm

AU - September, Alison V

PY - 2012

Y1 - 2012

N2 - Achilles tendinopathy (AT) is a degenerative condition for which several risk factors have been implicated including components of the inflammatory pathway. The aim was to assess functional variants within genes encoding components of the apoptosis signaling cascade and the effectiveness of a polygenic apoptosis profile to capture tendinopathy (TEN) risk

AB - Achilles tendinopathy (AT) is a degenerative condition for which several risk factors have been implicated including components of the inflammatory pathway. The aim was to assess functional variants within genes encoding components of the apoptosis signaling cascade and the effectiveness of a polygenic apoptosis profile to capture tendinopathy (TEN) risk

UR - http://www.sciencedirect.com/science/journal/07360266

U2 - 10.1002/jor.22144

DO - 10.1002/jor.22144

M3 - Article

SN - 0736-0266

VL - 30

SP - 1719

EP - 1724

JO - Journal of Orthopaedic Research

JF - Journal of Orthopaedic Research

IS - 11

ER -

The apoptosis pathway and the genetic predisposition to Achilles Tendinopathy

Abstract

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