The acceleration of ageing in older patients with cancer

Jaidyn Muhandiramge; Suzanne Orchard; Andrew Haydon; John Zalcberg

doi:10.1016/j.jgo.2020.09.010

The acceleration of ageing in older patients with cancer

Jaidyn Muhandiramge, Suzanne Orchard, Andrew Haydon, John Zalcberg

Research output: Contribution to journal › Review Article › Other › peer-review

21 Citations (Scopus)

Abstract

Older cancer survivors may experience ageing at an accelerated rate when compared to their similar-aged, cancer-free counterparts. Ageing is undoubtedly a significant risk factor for cancer. There is evidence to suggest, however, that this relationship may in fact be bidirectional, with cancer and its treatments contributing to the ageing process. In this review, we outline the current literature linking cancer and anti-cancer therapy to adverse ageing outcomes and explore what additional research is needed in order to conclusively define cancer and its treatment as an accelerator of ageing.

Original language	English
Pages (from-to)	343-351
Number of pages	9
Journal	Journal of Geriatric Oncology
Volume	12
Issue number	3
DOIs	https://doi.org/10.1016/j.jgo.2020.09.010
Publication status	Published - Apr 2021

Keywords

Accelerated ageing
Ageing
Cancer
Chronic disease
Cognitive decline
Frailty
Functional decline
Older patients

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jgo.2020.09.010

Cite this

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title = "The acceleration of ageing in older patients with cancer",

abstract = "Older cancer survivors may experience ageing at an accelerated rate when compared to their similar-aged, cancer-free counterparts. Ageing is undoubtedly a significant risk factor for cancer. There is evidence to suggest, however, that this relationship may in fact be bidirectional, with cancer and its treatments contributing to the ageing process. In this review, we outline the current literature linking cancer and anti-cancer therapy to adverse ageing outcomes and explore what additional research is needed in order to conclusively define cancer and its treatment as an accelerator of ageing.",

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AU - Muhandiramge, Jaidyn

AU - Orchard, Suzanne

AU - Haydon, Andrew

AU - Zalcberg, John

PY - 2021/4

Y1 - 2021/4

N2 - Older cancer survivors may experience ageing at an accelerated rate when compared to their similar-aged, cancer-free counterparts. Ageing is undoubtedly a significant risk factor for cancer. There is evidence to suggest, however, that this relationship may in fact be bidirectional, with cancer and its treatments contributing to the ageing process. In this review, we outline the current literature linking cancer and anti-cancer therapy to adverse ageing outcomes and explore what additional research is needed in order to conclusively define cancer and its treatment as an accelerator of ageing.

AB - Older cancer survivors may experience ageing at an accelerated rate when compared to their similar-aged, cancer-free counterparts. Ageing is undoubtedly a significant risk factor for cancer. There is evidence to suggest, however, that this relationship may in fact be bidirectional, with cancer and its treatments contributing to the ageing process. In this review, we outline the current literature linking cancer and anti-cancer therapy to adverse ageing outcomes and explore what additional research is needed in order to conclusively define cancer and its treatment as an accelerator of ageing.

KW - Accelerated ageing

KW - Ageing

KW - Cancer

KW - Chronic disease

KW - Cognitive decline

KW - Frailty

KW - Functional decline

KW - Older patients

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JO - Journal of Geriatric Oncology

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IS - 3

ER -

The acceleration of ageing in older patients with cancer

Abstract

Keywords

UN SDGs

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