Thalamic paraventricular nucleus lesions facilitate central amygdala neuronal responses to acute psychological stress

Sarah Spencer, James C Fox, Trevor A Day

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62 Citations (Scopus)


The thalamic paraventricular nucleus (PVT) is activated by stress and projects to forebrain structures directly implicated in processing stress-related information. Accordingly, it seems likely the PVT plays an important role in modulating stress responses. We examined effects of excitotoxic PVT lesions on forebrain Fos expression patterns normally elicited by an acute psychological stressor. PVT lesions significantly increased stress-induced Fos in a key stress-processing region, the central amygdala.
Original languageEnglish
Pages (from-to)234 - 237
Number of pages4
JournalBrain Research
Issue number2
Publication statusPublished - 2004

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