Tertiary lymphoid tissue in kidneys: understanding local immunity and inflammation

Kate J. Robson, A. Richard Kitching

Research output: Contribution to journalComment / DebateOtherpeer-review

Abstract

Tertiary lymphoid tissues are peripheral foci of immune activity that develop in kidneys and other peripheral organs in the context of chronic inflammation. In this issue of Kidney International, Sato and colleagues present a detailed characterization of tertiary lymphoid tissues in mouse and human kidneys in the context of acute kidney injury, chronic pyelonephritis, aging, and chronic kidney disease, showing the importance of nontraditional roles of B cells in the inflamed kidney microenvironment.

Original languageEnglish
Pages (from-to)280-283
Number of pages4
JournalKidney International
Volume98
Issue number2
DOIs
Publication statusPublished - Aug 2020

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