Tenofovir disoproxil fumarate rescue therapy following failure of both lamivudine and adefovir dipivoxil in chronic hepatitis B

Scott Patterson, Jacob George, Simone Strasser, Alice Lee, William Sievert, Amanda Nicoll, Paul Desmond, Stuart Roberts, Stephen Locarnini, Scott Bowden, Peter Angus

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138 Citations (Scopus)

Abstract

To determine the efficacy of tenofovir disoproxil fumarate (TDF) in adults with chronic hepatitis B virus (HBV) infection who had previously failed lamivudine (LAM) and had significant viral replication (HBV DNA >10a?? copies/ml if HBeAg positive, > 10a? copies/ml if HBeAg negative) despite at least 24 weeks of treatment with adefovir dipivoxil (ADV).
Original languageEnglish
Pages (from-to)247 - 254
Number of pages8
JournalGut
Volume60
Issue number2
DOIs
Publication statusPublished - 2011

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