Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development

Isabelle Manfroid, Xavier Caubit, Christophe Marcelle, Laurent Fasano

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Drosophila teashirt (tsh) is involved in the patterning of the trunk identity together with the Hox genes. In addition, it is also a player in the Wingless and the Hedgehog pathways. In birds and mammals, three Tshz genes are identified and the expression patterns for mouse Tshz1 and Tshz2 have been reported during embryogenesis. Recently, we showed that all three mouse Tshz genes can rescue the Drosophila tsh loss-of-function phenotype, indicating that the function of the teashirt genes has been conserved during evolution. Here we describe the expression pattern of chick TSHZ3 during embryogenesis. Chick TSHZ3 is expressed in several tissues including mesodermal derivatives, the central and peripheral nervous systems. Emphasis is laid on the dynamic expression occurring in regions of the somites and limbs where tendons develop. We show that TSHZ3 is activated in the somites by FGF8, a known inducer of the tendon marker SCX.
Original languageEnglish
Pages (from-to)908 - 912
Number of pages5
JournalGene Expression Patterns
Volume6
Issue number8
Publication statusPublished - 2006

Cite this

Manfroid, Isabelle ; Caubit, Xavier ; Marcelle, Christophe ; Fasano, Laurent. / Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development. In: Gene Expression Patterns. 2006 ; Vol. 6, No. 8. pp. 908 - 912.
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Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development. / Manfroid, Isabelle; Caubit, Xavier; Marcelle, Christophe; Fasano, Laurent.

In: Gene Expression Patterns, Vol. 6, No. 8, 2006, p. 908 - 912.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development

AU - Manfroid, Isabelle

AU - Caubit, Xavier

AU - Marcelle, Christophe

AU - Fasano, Laurent

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